Loop extrusion rules: the next generation
F Corsi, E Rusch, A Goloborodko - Current Opinion in Genetics & …, 2023 - Elsevier
Highlights•Cohesin loop extrusion is the key mechanism of 3D genome organization in
interphase of vertebrates.•Models of loop extrusion infer locations and dynamics of cohesin …
interphase of vertebrates.•Models of loop extrusion infer locations and dynamics of cohesin …
[HTML][HTML] Extrusion fountains are hallmarks of chromosome organization emerging upon zygotic genome activation
A Galitsyna, SV Ulianov, NS Bykov, M Veil, M Gao… - bioRxiv, 2023 - ncbi.nlm.nih.gov
The first activation of gene expression during development (zygotic genome activation, ZGA)
is accompanied by massive changes in chromosome organization. The connection between …
is accompanied by massive changes in chromosome organization. The connection between …
[HTML][HTML] Cohesin mediated loop extrusion from active enhancers form chromatin jets in C. elegans
J Kim, H Wang, S Ercan - bioRxiv, 2023 - ncbi.nlm.nih.gov
In mammals, cohesin and CTCF organize the 3D genome into topologically associated
domains (TADs) to regulate communication between cis-regulatory elements. However …
domains (TADs) to regulate communication between cis-regulatory elements. However …