Radiotherapy is a highly effective, targeted therapy for the management of cancer.
Technological innovations have enabled the direct integration of imaging technology into …

Oxygen deprivation (hypoxia) in non–small cell lung cancer (NSCLC) is an important factor
in treatment resistance and poor survival. Hypoxia is an attractive therapeutic target …

With the emergence of individualized medicine and the increasing amount and complexity of
available medical data, a growing need exists for the development of clinical decision …

Accurate volumetric assessment in non-small cell lung cancer (NSCLC) is critical for
adequately informing treatments. In this study we assessed the clinical relevance of a …

PURPOSE: The local site of relapse in non-small cell lung cancer (NSCLC) is primarily
located in the high FDG uptake region of the primary tumour prior to treatment. A phase II …

Purpose In this prospective National Cancer Institute–funded American College of
Radiology Imaging Network/Radiation Therapy Oncology Group cooperative group trial, we …

A paradigm shift from current population based medicine to personalized and participative
medicine is underway. This transition is being supported by the development of clinical …

Introduction: The 2-[18F]-Fluorodeoxyglucose (FDG) positron emission tomography
(PET/CT) has become an imaging tool for clinical assessment of tumor, node, metastasis in …

Modern radiation therapy techniques are exceptionally flexible in the deposition of radiation
dose in a target volume. Complex distributions of dose can be delivered reliably, so that the …

Purpose: Cancer is a multigene disease which arises as a result of mutational and
epigenetic changes coupled with activation of complex signaling networks. The use of …