Neuroprotective effects of coffee bioactive compounds: a review
K Socała, A Szopa, A Serefko, E Poleszak… - International journal of …, 2020 - mdpi.com
Coffee is one of the most widely consumed beverages worldwide. It is usually identified as a
stimulant because of a high content of caffeine. However, caffeine is not the only coffee …
stimulant because of a high content of caffeine. However, caffeine is not the only coffee …
Pharmacological modulation of Nrf2/HO-1 signaling pathway as a therapeutic target of Parkinson's disease
Y Wang, L Gao, J Chen, Q Li, L Huo, Y Wang… - Frontiers in …, 2021 - frontiersin.org
Parkinson's disease (PD) is a complex neurodegenerative disorder featuring both motor and
nonmotor symptoms associated with a progressive loss of dopaminergic neurons in the …
nonmotor symptoms associated with a progressive loss of dopaminergic neurons in the …
Neuroprotective effect of artichoke-based nanoformulation in sporadic Alzheimer's disease mouse model: focus on antioxidant, anti-inflammatory, and amyloidogenic …
The vast socio-economic impact of Alzheimer's disease (AD) has prompted the search for
new neuroprotective agents with good tolerability and safety profile. With its outstanding role …
new neuroprotective agents with good tolerability and safety profile. With its outstanding role …
[HTML][HTML] Oxidative stress, the blood–brain barrier and neurodegenerative diseases: The critical beneficial role of dietary antioxidants
J Feng, Y Zheng, M Guo, I Ares, M Martínez… - … Pharmaceutica Sinica B, 2023 - Elsevier
In recent years, growing awareness of the role of oxidative stress in brain health has
prompted antioxidants, especially dietary antioxidants, to receive growing attention as …
prompted antioxidants, especially dietary antioxidants, to receive growing attention as …
Natural antioxidants that act against Alzheimer's disease through modulation of the NRF2 pathway: a focus on their molecular mechanisms of action
Characterized by a complex pathophysiology that includes the intraneuronal formation of
neurofibrillary tangles and the extracellular deposition of β-amyloid plaques, Alzheimer's …
neurofibrillary tangles and the extracellular deposition of β-amyloid plaques, Alzheimer's …
Enhanced Antioxidant and Neuroprotective Properties of Pterostilbene (Resveratrol Derivative) in Amorphous Solid Dispersions
N Rosiak, E Tykarska, J Cielecka-Piontek - International Journal of …, 2024 - mdpi.com
In this study, amorphous solid dispersions (ASDs) of pterostilbene (PTR) with
polyvinylpyrrolidone polymers (PVP K30 and VA64) were prepared through milling, affirming …
polyvinylpyrrolidone polymers (PVP K30 and VA64) were prepared through milling, affirming …
p21-Activated kinase 1 (PAK1) in aging and longevity: An overview
M Amirthalingam, S Palanisamy, S Tawata - Ageing Research Reviews, 2021 - Elsevier
The p21-activated kinases (PAKs) belong to serine/threonine kinases family, regulated by∼
21 kDa small signaling G proteins RAC1 and CDC42. The mammalian PAK family …
21 kDa small signaling G proteins RAC1 and CDC42. The mammalian PAK family …
Synthesis of novel caffeic acid derivatives and their protective effect against hydrogen peroxide induced oxidative stress via Nrf2 pathway
X Peng, G Wu, A Zhao, K Huang, L Chai, B Natarajan… - Life sciences, 2020 - Elsevier
Aim This study was aimed to synthesize novel caffeic acid derivatives and evaluate their
potential applications for the treatment of oxidative stress associated disease. Main methods …
potential applications for the treatment of oxidative stress associated disease. Main methods …
Neuroprotective effects of methyl caffeate against hydrogen peroxide-induced cell damage: Involvement of caspase 3 and cathepsin D inhibition
D Jantas, J Chwastek, J Malarz, A Stojakowska… - Biomolecules, 2020 - mdpi.com
Finding effective neuroprotective strategies to combat various neurodegenerative disorders
still remain a clinically unmet need. Methyl caffeate (MC), a naturally occurring ester of …
still remain a clinically unmet need. Methyl caffeate (MC), a naturally occurring ester of …
Screening of the Anti-Neurodegenerative Activity of Caffeic Acid after Introduction into Inorganic Metal Delivery Systems to Increase Its Solubility as the Result of a …
A Stasiłowicz-Krzemień, N Rosiak… - International Journal of …, 2023 - mdpi.com
The proven anti-neurodegenerative properties of caffeic acid in vivo are limited due to its
poor solubility, which limits bioavailability. Therefore, caffeic acid delivery systems have …
poor solubility, which limits bioavailability. Therefore, caffeic acid delivery systems have …