[HTML][HTML] Traumatic brain injury: progress and challenges in prevention, clinical care, and research
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
Management of moderate to severe traumatic brain injury: an update for the intensivist
G Meyfroidt, P Bouzat, MP Casaer, R Chesnut… - Intensive care …, 2022 - Springer
Traumatic brain injury (TBI) remains one of the most fatal and debilitating conditions in the
world. Current clinical management in severe TBI patients is mainly concerned with …
world. Current clinical management in severe TBI patients is mainly concerned with …
[HTML][HTML] There is no such thing as a validated prediction model
Background Clinical prediction models should be validated before implementation in clinical
practice. But is favorable performance at internal validation or one external validation …
practice. But is favorable performance at internal validation or one external validation …
[HTML][HTML] Mechanical ventilation in patients with acute brain injury: recommendations of the European Society of Intensive Care Medicine consensus
C Robba, D Poole, M McNett, K Asehnoune… - Intensive care …, 2020 - Springer
Purpose To provide clinical practice recommendations and generate a research agenda on
mechanical ventilation and respiratory support in patients with acute brain injury (ABI) …
mechanical ventilation and respiratory support in patients with acute brain injury (ABI) …
Intracranial pressure monitoring in patients with acute brain injury in the intensive care unit (SYNAPSE-ICU): an international, prospective observational cohort study
C Robba, F Graziano, P Rebora, F Elli… - The Lancet …, 2021 - thelancet.com
Background The indications for intracranial pressure (ICP) monitoring in patients with acute
brain injury and the effects of ICP on patients' outcomes are uncertain. The aims of this study …
brain injury and the effects of ICP on patients' outcomes are uncertain. The aims of this study …
[HTML][HTML] Viscoelastic haemostatic assay augmented protocols for major trauma haemorrhage (ITACTIC): a randomized, controlled trial
K Baksaas-Aasen, LS Gall, J Stensballe… - Intensive care …, 2021 - Springer
Purpose Contemporary trauma resuscitation prioritizes control of bleeding and uses major
haemorrhage protocols (MHPs) to prevent and treat coagulopathy. We aimed to determine …
haemorrhage protocols (MHPs) to prevent and treat coagulopathy. We aimed to determine …
[HTML][HTML] Blood biomarkers on admission in acute traumatic brain injury: relations to severity, CT findings and care path in the CENTER-TBI study
Background Serum biomarkers may inform and improve care in traumatic brain injury (TBI).
We aimed to correlate serum biomarkers with clinical severity, care path and imaging …
We aimed to correlate serum biomarkers with clinical severity, care path and imaging …
[HTML][HTML] Casemix, management, and mortality of patients receiving emergency neurosurgery for traumatic brain injury in the Global Neurotrauma Outcomes Study: a …
D Clark, A Joannides, AO Adeleye, AH Bajamal… - The Lancet …, 2022 - thelancet.com
Background Traumatic brain injury (TBI) is increasingly recognised as being responsible for
a substantial proportion of the global burden of disease. Neurosurgical interventions are an …
a substantial proportion of the global burden of disease. Neurosurgical interventions are an …
Effect of continuous infusion of hypertonic saline vs standard care on 6-month neurological outcomes in patients with traumatic brain injury: the COBI randomized …
Importance Fluid therapy is an important component of care for patients with traumatic brain
injury, but whether it modulates clinical outcomes remains unclear. Objective To determine …
injury, but whether it modulates clinical outcomes remains unclear. Objective To determine …
Surgery versus conservative treatment for traumatic acute subdural haematoma: a prospective, multicentre, observational, comparative effectiveness study
TA van Essen, HF Lingsma, D Pisică, RD Singh… - The lancet …, 2022 - thelancet.com
Background Despite being well established, acute surgery in traumatic acute subdural
haematoma is based on low-grade evidence. We aimed to compare the effectiveness of a …
haematoma is based on low-grade evidence. We aimed to compare the effectiveness of a …