Mechanics and functional consequences of nuclear deformations

Y Kalukula, AD Stephens, J Lammerding… - … reviews Molecular cell …, 2022 - nature.com
As the home of cellular genetic information, the nucleus has a critical role in determining cell
fate and function in response to various signals and stimuli. In addition to biochemical …

Cell monolayers sense curvature by exploiting active mechanics and nuclear mechanoadaptation

M Luciano, SL Xue, WH De Vos, L Redondo-Morata… - Nature Physics, 2021 - nature.com
The early development of many organisms involves the folding of cell monolayers, but this
behaviour is difficult to reproduce in vitro; therefore, both mechanistic causes and effects of …

[HTML][HTML] Production of cultured meat from pig muscle stem cells

H Zhu, Z Wu, X Ding, MJ Post, R Guo, J Wang, J Wu… - Biomaterials, 2022 - Elsevier
Cultured meat is meat for consumption produced in a more sustainable way. It involves cell
harvesting and expansion, differentiation into myotubes, construction into muscle fibres and …

Cellular and molecular pathways controlling muscle size in response to exercise

M Attwaters, SM Hughes - The FEBS journal, 2022 - Wiley Online Library
From the discovery of ATP and motor proteins to synaptic neurotransmitters and growth
factor control of cell differentiation, skeletal muscle has provided an extreme model system …

Effect of boron-doped mesoporous bioactive glass nanoparticles on C2C12 cell viability and differentiation: potential for muscle tissue application

D Ege, Q Nawaz, AM Beltrán… - … Biomaterials Science & …, 2022 - ACS Publications
Mesoporous bioactive glasses (MBGs) exhibit a high surface area and a highly ordered
mesoporous structure. MBGs have potential for both hard and soft tissue engineering …

Stiffness anisotropy coordinates supracellular contractility driving long-range myotube-ECM alignment

NP Skillin, BE Kirkpatrick, KM Herbert, BR Nelson… - Science …, 2024 - science.org
The ability of cells to organize into tissues with proper structure and function requires the
effective coordination of proliferation, migration, polarization, and differentiation across …

Bioinspired electrospun dECM scaffolds guide cell growth and control the formation of myotubes

MM Smoak, KJ Hogan, KJ Grande-Allen, AG Mikos - Science Advances, 2021 - science.org
While skeletal muscle has a high capacity for endogenous repair in acute injuries,
volumetric muscle loss can leave long-lasting or permanent structural and functional deficits …

Brush-induced orientation of collagen fibers in layer-by-layer nanofilms: A simple method for the development of human muscle fibers

MH Iqbal, FJR Revana, E Pradel, V Gribova… - ACS …, 2022 - ACS Publications
The engineering of skeletal muscle tissue, a highly organized structure of myotubes, is
promising for the treatment of muscle injuries and muscle diseases, for replacement, or for …

Development of cultivable alginate fibers for an ideal cell-cultivated meat scaffold and production of hybrid cultured meat

JW Seo, WK Jung, YH Park, H Bae - Carbohydrate Polymers, 2023 - Elsevier
Slaughtering animals for meat pose several challenges, including environmental pollution
and ethical concerns. Scaffold-based cell-cultivated meat has been proposed as a solution …

A 3D, magnetically actuated, aligned collagen fiber hydrogel platform recapitulates physical microenvironment of myoblasts for enhancing myogenesis

N Shi, Y Li, L Chang, G Zhao, G Jin, Y Lyu… - Small …, 2021 - Wiley Online Library
Many cell responses that underlie the development, maturation, and function of tissues are
guided by the architecture and mechanical loading of the extracellular matrix (ECM) …