International Union of Basic and Clinical Pharmacology. CX. Classification of receptors for 5-hydroxytryptamine; pharmacology and function
5-HT receptors expressed throughout the human body are targets for established
therapeutics and various drugs in development. Their diversity of structure and function …
therapeutics and various drugs in development. Their diversity of structure and function …
Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications
RZ Goldstein, ND Volkow - Nature reviews neuroscience, 2011 - nature.com
The loss of control over drug intake that occurs in addiction was initially believed to result
from disruption of subcortical reward circuits. However, imaging studies in addictive …
from disruption of subcortical reward circuits. However, imaging studies in addictive …
[HTML][HTML] Cortico-striatal-thalamic loop circuits of the orbitofrontal cortex: promising therapeutic targets in psychiatric illness
Corticostriatal circuits through the orbitofrontal cortex (OFC) play key roles in complex
human behaviors such as evaluation, affect regulation and reward-based decision-making …
human behaviors such as evaluation, affect regulation and reward-based decision-making …
Interoception in anxiety and depression
We review the literature on interoception as it relates to depression and anxiety, with a focus
on belief, and alliesthesia. The connection between increased but noisy afferent …
on belief, and alliesthesia. The connection between increased but noisy afferent …
Brain anatomy alterations associated with Social Networking Site (SNS) addiction
This study relies on knowledge regarding the neuroplasticity of dual-system components
that govern addiction and excessive behavior and suggests that alterations in the grey …
that govern addiction and excessive behavior and suggests that alterations in the grey …
Similarities and differences between pathological gambling and substance use disorders: a focus on impulsivity and compulsivity
RF Leeman, MN Potenza - Psychopharmacology, 2012 - Springer
Rationale Pathological gambling (PG) has recently been considered as a “behavioral” or
nonsubstance addiction. A comparison of the characteristics of PG and substance use …
nonsubstance addiction. A comparison of the characteristics of PG and substance use …
What are the specific vs. generalized effects of drugs of abuse on neuropsychological performance?
MJ Fernández-Serrano, M Pérez-García… - Neuroscience & …, 2011 - Elsevier
Most substance abusers simultaneously use and abuse more than one substance, even
when there is a clear drug of choice. This pattern creates a great challenge in relating …
when there is a clear drug of choice. This pattern creates a great challenge in relating …
The error-related negativity (ERN) and psychopathology: Toward an endophenotype
DM Olvet, G Hajcak - Clinical psychology review, 2008 - Elsevier
The ERN is a negative deflection in the event-related potential that peaks approximately 50
ms after the commission of an error. The ERN is thought to reflect early error-processing …
ms after the commission of an error. The ERN is thought to reflect early error-processing …
The neurobiology of pathological gambling and drug addiction: an overview and new findings
MN Potenza - … Transactions of the Royal Society B …, 2008 - royalsocietypublishing.org
Gambling is a prevalent recreational behaviour. Approximately 5% of adults have been
estimated to experience problems with gambling. The most severe form of gambling …
estimated to experience problems with gambling. The most severe form of gambling …
Gray matter abnormalities in Internet addiction: a voxel-based morphometry study
BACKGROUND: This study aims to investigate brain gray matter density (GMD) changes in
adolescents with Internet addiction (IA) using voxel-based morphometry (VBM) analysis on …
adolescents with Internet addiction (IA) using voxel-based morphometry (VBM) analysis on …