Although stem/progenitor cell therapy shows potential for myocardial infarction repair,
enhancing the therapeutic efficacy could be achieved through additional genetic …

Reperfusion therapy after acute myocardial infarction can induce myocardial ischemia-
reperfusion injury (IRI). Novel evidence has illustrated that N6-methyladenosine (m6A) …

Introduction: Myocardial infarction (MI) is the leading cause of death. When MI is not lethal,
heart failure (HF) is a major consequence with high prevalence and poor prognosis. The …

Activin/SMAD signaling in human embryonic stem cells (hESCs) ensures NANOG
expression and stem cell pluripotency. In the presence of Wnt ligand, the Activin/SMAD …

Cardiomyocytes differentiated from human‐induced pluripotent stem cells (hiPSCs) hold
great potential for therapy of heart diseases. However, the underlying mechanisms of its …

Relatively quiescent tissues like salivary glands (SGs) respond to stimuli such as injury to
expand, replace and regenerate. Resident stem/progenitor cells are key in this process …

Yes‑associated protein (YAP) serves an essential role in tumorigenesis. However, the
potential role and the molecular mechanism underlying the effect of YAP on hepatocellular …

Hippo signaling is a conserved pathway and plays important roles in controlling cell
proliferation and differentiation. As a critical component of the Hippo pathway in mammals …

Apoptosis and inflammation were the main hallmarks of sepsis-induced cardiomyopathy
(SIC). Yes-associated protein isoform 1 (Yap1) and miR-484 were involved in mitochondrial …

Wood frogs (Rana sylvatica) display well-developed anoxia tolerance as one component of
their capacity to endure prolonged whole-body freezing during the winter months. Under …