[HTML][HTML] The WHO 2021 Classification of Central Nervous System tumours: a practical update on what neurosurgeons need to know—a minireview
SH Torp, O Solheim, AJ Skjulsvik - Acta Neurochirurgica, 2022 - Springer
Abstract Background The World Health Organization (WHO) Classification of Tumours, also
known as WHO Blue Books, represents an international standardised tool in the diagnostic …
known as WHO Blue Books, represents an international standardised tool in the diagnostic …
The 2021 WHO classification of tumors of the central nervous system: a summary
The fifth edition of the WHO Classification of Tumors of the Central Nervous System (CNS),
published in 2021, is the sixth version of the international standard for the classification of …
published in 2021, is the sixth version of the international standard for the classification of …
A molecularly integrated grade for meningioma
Background Meningiomas are the most common primary intracranial tumor in adults.
Clinical care is currently guided by the World Health Organization (WHO) grade assigned to …
Clinical care is currently guided by the World Health Organization (WHO) grade assigned to …
Molecular alterations in meningioma: prognostic and therapeutic perspectives
The mutational landscape of meningioma has expanded following the use of the new
genetic sequencing approaches. Novel mutations have been characterized and reveal their …
genetic sequencing approaches. Novel mutations have been characterized and reveal their …
Loss of H3K27me3 in meningiomas
F Nassiri, JZ Wang, O Singh, S Karimi… - Neuro …, 2021 - academic.oup.com
Background There is a critical need for objective and reliable biomarkers of outcome in
meningiomas beyond WHO classification. Loss of H3K27me3 has been reported as a …
meningiomas beyond WHO classification. Loss of H3K27me3 has been reported as a …
H3K27me3 loss indicates an increased risk of recurrence in the Tübingen meningioma cohort
F Behling, C Fodi, I Gepfner-Tuma… - Neuro …, 2021 - academic.oup.com
Background A loss of the trimethylation of lysine 27 of histone H3 (H3K27me3) in
meningioma has been recently suggested as an adjunct to identify subsets of higher risk of …
meningioma has been recently suggested as an adjunct to identify subsets of higher risk of …
[HTML][HTML] Impact of H3K27 trimethylation loss in meningiomas: a meta-analysis
G Cello, RV Patel, JT McMahon, S Santagata… - Acta neuropathologica …, 2023 - Springer
Trimethylation of lysine 27 on histone 3 (H3K27me3) loss has been implicated in worse
prognoses for patients with meningiomas. However, there have been challenges in …
prognoses for patients with meningiomas. However, there have been challenges in …
[HTML][HTML] Surgical strategies for intracranial meningioma in the molecular era
Introduction Surgical resection has long been the treatment of choice for meningiomas and
is considered curative in many cases. Indeed, the extent of resection (EOR) remains a …
is considered curative in many cases. Indeed, the extent of resection (EOR) remains a …
A current review of spinal meningiomas: epidemiology, clinical presentation and management
AA Elsamadicy, BC Reeves, S Craft… - Journal of neuro …, 2023 - Springer
Purpose To provide an up-to-date review of the epidemiology, histopathology, molecular
biology, and etiology of spinal meningiomas, as well as discuss the clinical presentation …
biology, and etiology of spinal meningiomas, as well as discuss the clinical presentation …
Spatial genomic, biochemical and cellular mechanisms underlying meningioma heterogeneity and evolution
Intratumor heterogeneity underlies cancer evolution and treatment resistance, but targetable
mechanisms driving intratumor heterogeneity are poorly understood. Meningiomas are the …
mechanisms driving intratumor heterogeneity are poorly understood. Meningiomas are the …