The ancestral and industrialized gut microbiota and implications for human health

ED Sonnenburg, JL Sonnenburg - Nature Reviews Microbiology, 2019 - nature.com
Human-associated microbial communities have adapted to environmental pressures. Doses
of antibiotics select for a community with increased antibiotic resistance, inflammation is …

Exploring the human microbiome: the potential future role of next-generation sequencing in disease diagnosis and treatment

MA Malla, A Dubey, A Kumar, S Yadav… - Frontiers in …, 2019 - frontiersin.org
The interaction between the human microbiome and immune system has an effect on
several human metabolic functions and impacts our well-being. Additionally, the interaction …

[HTML][HTML] Reconstruction of ancient microbial genomes from the human gut

MC Wibowo, Z Yang, M Borry, A Hübner, KD Huang… - Nature, 2021 - nature.com
Loss of gut microbial diversity,,,,–in industrial populations is associated with chronic
diseases, underscoring the importance of studying our ancestral gut microbiome. However …

The Prevotella copri complex comprises four distinct clades underrepresented in westernized populations

A Tett, KD Huang, F Asnicar, H Fehlner-Peach… - Cell host & …, 2019 - cell.com
Prevotella copri is a common human gut microbe that has been both positively and
negatively associated with host health. In a cross-continent meta-analysis exploiting> 6,500 …

The human microbiome in evolution

ER Davenport, JG Sanders, SJ Song, KR Amato… - BMC biology, 2017 - Springer
The trillions of microbes living in the gut—the gut microbiota—play an important role in
human biology and disease. While much has been done to explore its diversity, a full …

Captivity humanizes the primate microbiome

JB Clayton, P Vangay, HU Huang… - Proceedings of the …, 2016 - National Acad Sciences
The primate gastrointestinal tract is home to trillions of bacteria, whose composition is
associated with numerous metabolic, autoimmune, and infectious human diseases …

The first 1000 cultured species of the human gastrointestinal microbiota

M Rajilić-Stojanović, WM De Vos - FEMS microbiology reviews, 2014 - academic.oup.com
The microorganisms that inhabit the human gastrointestinal tract comprise a complex
ecosystem with functions that significantly contribute to our systemic metabolism and have …

Gut microbiome of the Hadza hunter-gatherers

SL Schnorr, M Candela, S Rampelli, M Centanni… - Nature …, 2014 - nature.com
Human gut microbiota directly influences health and provides an extra means of adaptive
potential to different lifestyles. To explore variation in gut microbiota and to understand how …

Starving our microbial self: the deleterious consequences of a diet deficient in microbiota-accessible carbohydrates

ED Sonnenburg, JL Sonnenburg - Cell metabolism, 2014 - cell.com
The gut microbiota of a healthy person may not be equivalent to a healthy microbiota. It is
possible that the Western microbiota is actually dysbiotic and predisposes individuals to a …

Subsistence strategies in traditional societies distinguish gut microbiomes

AJ Obregon-Tito, RY Tito, J Metcalf… - Nature …, 2015 - nature.com
Recent studies suggest that gut microbiomes of urban-industrialized societies are different
from those of traditional peoples. Here we examine the relationship between lifeways and …