Alkoxy radicals are highly reactive species that have long been recognized as versatile
intermediates in organic synthesis. However, their development has long been impeded due …

In the pursuit of new pharmaceuticals and agrochemicals, chemists in the life science
industry require access to mild and robust synthetic methodologies to systematically modify …

The applications of fluorine in drug design continue to expand, facilitated by an improved
understanding of its effects on physicochemical properties and the development of synthetic …

The electronic properties and relatively small size of fluorine endow it with considerable
versatility as a bioisostere and it has found application as a substitute for lone pairs of …

Over the past decade, the most significant, conceptual advances in the field of fluorination
were enabled most prominently by organo‐and transition‐metal catalysis. The most …

Die wichtigsten konzeptionellen Fortschritt auf dem Gebiet der Fluorierungen der letzten
zehn Jahre wurden durch die Organo‐und Übergangsmetallkatalyse ermöglicht. Die …

The past 30 years have witnessed a period of significant expansion in the use of
halogenated compounds in the field of agrochemical research and development. The …

The ever-growing number of fluorinated compounds in medicinal and agrochemical
applications has led to a remarkable positive emulation in research. The last few years have …

Fluorine, the most electronegative element plays nowadays a key role in pharmaceutical,
agrochemical and material sciences. About 20% of all pharmaceuticals and about 30% of …

A simple trifluoromethoxylation method enables non‐directed functionalization of C− H
bonds on a range of substrates, providing access to aryl trifluoromethyl ethers. This light …