[HTML][HTML] Multiple sclerosis: pathogenesis, symptoms, diagnoses and cell-based therapy
Multiple sclerosis (MS) is a chronic inflammatory disease characterized by central nervous
system (CNS) lesions that can lead to severe physical or cognitive disability as well as …
system (CNS) lesions that can lead to severe physical or cognitive disability as well as …
The immunogenetics of multiple sclerosis: A comprehensive review
JA Hollenbach, JR Oksenberg - Journal of autoimmunity, 2015 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system and
common cause of non-traumatic neurological disability in young adults. The likelihood for an …
common cause of non-traumatic neurological disability in young adults. The likelihood for an …
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
Nature, 2011 - nature.com
Multiple sclerosis is a common disease of the central nervous system in which the interplay
between inflammatory and neurodegenerative processes typically results in intermittent …
between inflammatory and neurodegenerative processes typically results in intermittent …
Class II HLA interactions modulate genetic risk for multiple sclerosis
Nature genetics, 2015 - nature.com
Association studies have greatly refined the understanding of how variation within the
human leukocyte antigen (HLA) genes influences risk of multiple sclerosis. However, the …
human leukocyte antigen (HLA) genes influences risk of multiple sclerosis. However, the …
Sex and gender issues in multiple sclerosis
HF Harbo, R Gold, M Tintoré - Therapeutic advances in …, 2013 - journals.sagepub.com
Multiple sclerosis (MS) is universally found to be more prevalent in women than men. This
has led to extensive studies of differences in the immune system or nervous system between …
has led to extensive studies of differences in the immune system or nervous system between …
Multiple sclerosis: risk factors, prodromes, and potential causal pathways
Multiple sclerosis (MS) is a common, complex neurological disease. The precise aetiology of
MS is not yet known, although epidemiological data indicate that both genetic and …
MS is not yet known, although epidemiological data indicate that both genetic and …
The genetics of multiple sclerosis: an up‐to‐date review
Multiple sclerosis (MS) is a prevalent inflammatory disease of the central nervous system
that often leads to disability in young adults. Treatment options are limited and often only …
that often leads to disability in young adults. Treatment options are limited and often only …
Genetics of multiple sclerosis: lessons from polygenicity
A Goris, M Vandebergh, JL McCauley… - The Lancet …, 2022 - thelancet.com
Large-scale mapping studies have identified 236 independent genetic variants associated
with an increased risk of multiple sclerosis. However, none of these variants are found …
with an increased risk of multiple sclerosis. However, none of these variants are found …
Multiple sclerosis relapses: epidemiology, outcomes and management. A systematic review
T Kalincik - Neuroepidemiology, 2015 - karger.com
Relapses (episodic exacerbations of neurological signs or symptoms) are a defining feature
of relapsing-remitting multiple sclerosis (MS), the most prevalent MS phenotype. While their …
of relapsing-remitting multiple sclerosis (MS), the most prevalent MS phenotype. While their …
Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis
LF Barcellos, S Sawcer, PP Ramsay… - Human molecular …, 2006 - academic.oup.com
Variation in major histocompatibility complex genes on chromosome 6p21. 3, specifically the
human leukocyte antigen HLA-DR2 or DRB1* 1501-DQB1* 0602 extended haplotype …
human leukocyte antigen HLA-DR2 or DRB1* 1501-DQB1* 0602 extended haplotype …