As the professional antigen-presenting cells of the immune system, dendritic cells (DCs)
sense the microenvironment and shape the ensuing adaptive immune response. DCs can …

New therapies that promote antitumour immunity have been recently developed. Most of
these immunomodulatory approaches have focused on enhancing T-cell responses, either …

Dendritic cells (DCs) can be viewed as translators between innate and adaptive immunity.
They integrate signals derived from tissue infection or damage and present processed …

Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid
haematopoiesis that form an essential interface between the innate sensing of pathogens …

Dendritic cells (DCs) possess the ability to integrate information about their environment and
communicate it to other leukocytes, shaping adaptive and innate immunity. Over the years, a …

INTRODUCTION Dendritic cells (DCs) and monocytes consist of multiple specialized
subtypes that play a central role in pathogen sensing, phagocytosis, and antigen …

PD-L1/PD-1 blocking antibodies have demonstrated therapeutic efficacy across a range of
human cancers. Extending this benefit to a greater number of patients, however, will require …

Dendritic cells have the ability to efficiently present internalized antigens on major
histocompatibility complex (MHC) I molecules. This process is termed cross-presentation …

Adoptive cell transfer (ACT) using chimeric antigen receptor (CAR)‐modified T cells can
induce durable remissions in patients with refractory B‐lymphoid cancers. By contrast …

Large numbers of melanoma lesions develop resistance to targeted inhibition of mutant
BRAF or fail to respond to checkpoint blockade. We explored whether modulation of …