Cardiovascular disease is a leading cause of death worldwide and accounts for> 17.3
million deaths per year, with an estimated increase in incidence to 23.6 million by 2030 …

Arterial stiffening is the principal cause of increasing systolic pressure with advancing years
and in patients with arterial hypertension. It is associated with progressive arterial dilation …

Arterial stiffness has independent predictive value for cardiovascular events. We review data
concerning the heritability of arterial stiffness, and propose an integrated view of the …

An experimental in vivo model of aortic aneurysm was established by perfusing an isolated
segment of rat abdominal aorta with pancreatic elastase. Ten rats were used in each …

High blood pressure is responsible for the modulation of blood vessel morphology and
function. Arterial hypertension is considered to play a significant role in atherosclerotic …

Blood vessels are permanently subjected to mechanical forces in the form of stretch,
encompassing cyclic mechanical strain due to the pulsatile nature of blood flow, and shear …

Vascular remodeling is the result of a close interplay of changes in vascular tone and
structure. In this review, the role of angiotension-converting enzyme (ACE) and the impact of …

Vascular remodeling is central to the pathophysiology of hypertension and atherosclerosis.
Recent evidence suggests that vasoconstrictive substances, such as angiotensin II (AII), may …

Background. The aim of the study was to determine which, and to what extent,
haemodynamic parameters contribute to the remodelling of the venous limb of the Brescia …

Background There is evidence for increased formation of free radicals in patients with
hypertension, raising the possibility that NO is inactivated by free radicals, which impairs …