Stem cell therapy: from idea to clinical practice

M Mousaei Ghasroldasht, J Seok, HS Park… - International journal of …, 2022 - mdpi.com
Regenerative medicine is a new and promising mode of therapy for patients who have
limited or no other options for the treatment of their illness. Due to their pleotropic therapeutic …

Comprehensive bibliometric analysis of stem cell research in Alzheimer's disease from 2004 to 2022

R Wang, Y Zhu, LF Qin, ZG Xu, XR Gao… - Dementia and Geriatric …, 2023 - karger.com
Introduction: Stem cell-based regenerative medicine has provided an excellent opportunity
to investigate therapeutic strategies and innovative treatments for Alzheimer's disease (AD) …

Mesenchymal stem cell-derived exosomes ameliorate Alzheimer's disease pathology and improve cognitive deficits

YA Chen, CH Lu, CC Ke, SJ Chiu, FS Jeng, CW Chang… - Biomedicines, 2021 - mdpi.com
The accumulation of extracellular β-amyloid (Aβ) plaques within the brain is unique to
Alzheimer's disease (AD) and thought to induce synaptic deficits and neuronal loss. Optimal …

Stem cells-derived exosomes alleviate neurodegeneration and Alzheimer's pathogenesis by ameliorating neuroinflamation, and regulating the associated molecular …

MI Khan, ES Jeong, MZ Khan, JH Shin, JD Kim - Scientific Reports, 2023 - nature.com
Amyloid beta (Aβ) aggregation and tau hyper phosphorylation (p-tau) are key molecular
factors in Alzheimer's disease (AD). The abnormal formation and accumulation of Aβ and p …

Nanotherapeutic and stem cell therapeutic strategies in neurodegenerative diseases: A promising therapeutic approach

M Wei, Z Yang, S Li, W Le - International journal of nanomedicine, 2023 - Taylor & Francis
Neurodegeneration is characterized by progressive, disabling, and incurable neurological
disorders with the massive loss of specific neurons. As one of the most promising potential …

Nerve regeneration using decellularized tissues: challenges and opportunities

M Mahdian, TS Tabatabai, Z Abpeikar… - Frontiers in …, 2023 - frontiersin.org
In tissue engineering, the decellularization of organs and tissues as a biological scaffold
plays a critical role in the repair of neurodegenerative diseases. Various protocols for cell …

Assessing causal relationship between circulating cytokines and age-related neurodegenerative diseases: a bidirectional two-sample Mendelian randomization …

Z Yin, J Chen, M Xia, X Zhang, Y Li, Z Chen, Q Bao… - Scientific Reports, 2023 - nature.com
Numerous studies have reported that circulating cytokines (CCs) are linked to age-related
neurodegenerative diseases (ANDDs); however, there is a lack of systematic investigation …

The role of neuroinflammation in neurodegenerative diseases: current understanding and future therapeutic targets

A Adamu, S Li, F Gao, G Xue - Frontiers in Aging Neuroscience, 2024 - frontiersin.org
Neuroinflammation refers to a highly complicated reaction of the central nervous system
(CNS) to certain stimuli such as trauma, infection, and neurodegenerative diseases. This is a …

[HTML][HTML] Emerging polymeric biomaterials and manufacturing-based tissue engineering approaches for neuro regeneration-A critical review on recent effective …

A Akhtar, VF Rad, AR Moradi, M Yar… - Smart Materials in …, 2023 - Elsevier
The nervous system is a crucial part of the human body that is damaged by traumatic injury,
stroke, and neurodegenerative diseases. Recent studies also have shown that …

Therapeutic efficacy and promise of stem cell-derived extracellular vesicles in Alzheimer's disease and other aging-related disorders

HA Rather, S Almousa, S Craft, G Deep - Ageing Research Reviews, 2023 - Elsevier
The term extracellular vesicles (EVs) refers to a variety of heterogeneous nanovesicles
secreted by almost all cell types, primarily for intercellular communication and maintaining …