Use of defined TLR ligands as adjuvants within human vaccines

MS Duthie, HP Windish, CB Fox… - Immunological …, 2011 - Wiley Online Library
Our improved understanding of how innate immune responses can be initiated and how
they can shape adaptive B‐and T‐cell responses is having a significant impact on vaccine …

Vaccines for visceral leishmaniasis: A review

K Jain, NK Jain - Journal of immunological methods, 2015 - Elsevier
Visceral leishmaniasis, which is also known as Kala-Azar, is one of the most severely
neglected tropical diseases recognized by the World Health Organization (WHO). The threat …

Novel areas for prevention and control of canine leishmaniosis

G Miró, C Petersen, L Cardoso, P Bourdeau… - Trends in …, 2017 - cell.com
There have been multiple recent advances regarding tools for the control and prevention of
canine leishmaniosis (CanL), including new preventative vaccines. In this review, these …

Current status on prevention and treatment of canine leishmaniasis

RM Reguera, M Moran, Y Perez-Pertejo… - Veterinary …, 2016 - Elsevier
Canine leishmaniasis (CanL) is a parasite-borne disease mainly induced by Leishmania
infantum in the Old World and Leishmania chagasi (infantum) in the New World. CanL is a …

Vaccines to combat the neglected tropical diseases

JM Bethony, RN Cole, X Guo, S Kamhawi… - Immunological …, 2011 - Wiley Online Library
The neglected tropical diseases (NTDs) represent a group of parasitic and related infectious
diseases such as amebiasis, Chagas disease, cysticercosis, echinococcosis, hookworm …

Case study for a vaccine against leishmaniasis

J Alvar, SL Croft, P Kaye, A Khamesipour, S Sundar… - Vaccine, 2013 - Elsevier
Leishmaniasis in many ways offers a unique vaccine case study. Two reasons for this are
that leishmaniasis is a disease complex caused by several different species of parasite that …

Leishmaniosis

G Baneth, C Petersen, L Solano-Gallego… - … Infectious Diseases of …, 2021 - Elsevier
First Described: The cause of visceral leishmaniasis was first described in India in 1903
(separately by William Leishman and Charles Donovan).• Causes: Canine and feline …

The development and clinical evaluation of second-generation leishmaniasis vaccines

MS Duthie, VS Raman, FM Piazza, SG Reed - Vaccine, 2012 - Elsevier
Infection with Leishmania parasites results in a range of clinical manifestations and
outcomes. Control of Leishmania parasite transmission is extremely difficult due to the large …

Leishmaniasis and various immunotherapeutic approaches

Y Taslimi, F Zahedifard, S Rafati - Parasitology, 2018 - cambridge.org
Leishmaniasis is a vector-borne infectious disease caused by multiple Leishmania (L.)
species with diverse clinical manifestations. There is currently no vaccine against any form …

Immunotherapy and immunochemotherapy in visceral leishmaniasis: promising treatments for this neglected disease

BM Roatt, RDO Aguiar-Soares, W Coura-Vital… - Frontiers in …, 2014 - frontiersin.org
Leishmaniasis has several clinical forms: self-healing or chronic cutaneous leishmaniasis or
post-kala-azar dermal leishmaniasis; mucosal leishmaniasis; visceral leishmaniasis (VL) …