Podocytopathies are kidney diseases in which direct or indirect podocyte injury drives
proteinuria or nephrotic syndrome. In children and young adults, genetic variants in> 50 …

Idiopathic nephrotic syndrome newly affects 1–3 per 100,000 children per year.
Approximately 85% of cases show complete remission of proteinuria following …

Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …

The incidence of idiopathic nephrotic syndrome (NS) is 1· 15–16· 9 per 100 000 children,
varying by ethnicity and region. The cause remains unknown but the pathogenesis of …

In November 2017, the Kidney Disease: Improving Global Outcomes (KDIGO) initiative
brought a diverse panel of experts in glomerular diseases together to discuss the 2012 …

More than 85% of children and adolescents (majority between 1–12 years old) with
idiopathic nephrotic syndrome show complete remission of proteinuria following daily …

Background: Steroid resistant nephrotic syndrome (SRNS) is a rare condition, accounting for
10–15% of all children with idiopathic nephrotic syndrome. SRNS can be caused by genetic …

Primary Coenzyme Q10 (CoQ10) deficiency is an ultra-rare disorder caused by defects in
genes involved in CoQ10 biosynthesis leading to multidrug-resistant nephrotic syndrome as …

Background In recent years, B-cell dysfunction has been found to play an important role in
the pathogenesis of primary nephrotic syndrome (PNS). B cells play a pathogenic role by …

Steroid-resistant nephrotic syndrome (SRNS) remains a challenge for paediatric
nephrologists. SRNS is viewed as a heterogeneous disease entity including immune-based …