Alzheimer's disease, a major and increasing global health challenge, is an irreversible,
progressive form of dementia, associated with an ongoing decline of brain functioning. The …

Edible seaweeds are rich in bioactive antioxidants, soluble dietary fibers, proteins, minerals,
vitamins, phytochemicals, and polyunsaturated fatty acids. Although previously the …

Acetylcholinesterase (AChE) enzyme inhibition is an important target for the management of
Alzheimer disease (AD) and AChE inhibitors are the main stay drugs for its management …

Rosemary (Rosmarinus officinalis L.) is one of the most economically important species of
the family Lamiaceae. Native to the Mediterranean region, the plant is now widely distributed …

Background. Cholinesterases are a group of serine hydrolases that split the neurotransmitter
acetylcholine (ACh) and terminate its action. Of the two types, butyrylcholinesterase and …

Both Alzheimer's disease (AD) and Type 2 diabetes mellitus (T2DM) share the presence of
systemic and neuro-inflammation, enhanced production and accumulation of β-amyloid …

Alzheimer's disease (AD) is characterized by a progressive phenotypic downregulation of
markers within cholinergic basal forebrain (CBF) neurons, frank CBF cell loss and reduced …

Abstract The cholinesterase inhibitors (ChE-Is) attenuate the cholinergic deficit underlying
the cognitive and neuropsychiatric dysfunctions in patients with AD. Inhibition of brain …

Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

Methylene Blue (MB), following its introduction to biology in the 19th century by Ehrlich, has
found uses in various areas of medicine and biology. At present, MB is the first line of …