Cancer combination therapies by angiogenesis inhibitors; a comprehensive review

MJ Ansari, D Bokov, A Markov, AT Jalil… - Cell Communication and …, 2022 - Springer
Abnormal vasculature is one of the most conspicuous traits of tumor tissue, largely
contributing to tumor immune evasion. The deregulation mainly arises from the potentiated …

Molecular pharmacology of VEGF-A isoforms: binding and signalling at VEGFR2

CJ Peach, VW Mignone, MA Arruda… - International journal of …, 2018 - mdpi.com
Vascular endothelial growth factor-A (VEGF-A) is a key mediator of angiogenesis, signalling
via the class IV tyrosine kinase receptor family of VEGF Receptors (VEGFRs). Although …

Engineering bacteria‐activated multifunctionalized hydrogel for promoting diabetic wound healing

Y Lu, H Li, J Wang, M Yao, Y Peng, T Liu… - Advanced Functional …, 2021 - Wiley Online Library
Engineering therapeutic angiogenesis in impaired tissues is critical for chronic wound
healing. Materials can be engineered to deliver specific biological cues that enhance …

Monocytes deposit migrasomes to promote embryonic angiogenesis

C Zhang, T Li, S Yin, M Gao, H He, Y Li, D Jiang… - Nature Cell …, 2022 - nature.com
Pro-angiogenic factors are key regulators of angiogenesis. Here we report that highly
migratory cells patrol the area of capillary formation in chick embryo chorioallantoic …

Light‐controlled growth factors release on tetrapodal ZnO‐incorporated 3D‐printed hydrogels for developing smart wound scaffold

L Siebert, E Luna‐Cerón… - Advanced functional …, 2021 - Wiley Online Library
Advanced wound scaffolds that integrate active substances to treat chronic wounds have
gained significant recent attention. While wound scaffolds and advanced functionalities have …

VEGF-A in cardiomyocytes and heart diseases

M Braile, S Marcella, L Cristinziano… - International Journal of …, 2020 - mdpi.com
The vascular endothelial growth factor (VEGF), a homodimeric vasoactive glycoprotein, is
the key mediator of angiogenesis. Angiogenesis, the formation of new blood vessels, is …

[HTML][HTML] The molecular mechanisms of hemodialysis vascular access failure

A Brahmbhatt, A Remuzzi, M Franzoni, S Misra - Kidney international, 2016 - Elsevier
The arteriovenous fistula has been used for more than 50 years to provide vascular access
for patients undergoing hemodialysis. More than 1.5 million patients worldwide have end …

Potential role of natural compounds as anti-angiogenic agents in cancer

MK Shanmugam, S Warrier, AP Kumar… - Current vascular …, 2017 - ingentaconnect.com
Background: Neovascularization, also known as angiogenesis, is the process of capillary
sprouting from pre-existing blood vessels. This physiological process is a hallmark event in …

Effect of biochemical and biomechanical factors on vascularization of kidney organoid-on-a-chip

HN Lee, YY Choi, JW Kim, YS Lee, JW Choi, T Kang… - Nano …, 2021 - Springer
Kidney organoids derived from the human pluripotent stem cells (hPSCs) recapitulating
human kidney are the attractive tool for kidney regeneration, disease modeling, and drug …

Biomaterials for bioprinting microvasculature

RW Barrs, J Jia, SE Silver, M Yost, Y Mei - Chemical reviews, 2020 - ACS Publications
Microvasculature functions at the tissue and cell level, regulating local mass exchange of
oxygen and nutrient-rich blood. While there has been considerable success in the …