Background: The epidemiology of nasopharyngeal carcinoma (NPC) has long been a
source of fascination due to the malignancy's striking geographic distribution, the …

Simple Summary Growing evidence indicates that blood-count-based compound scores
could be used as prognostic biomarkers in cancer as reflectors of uncontrolled inflammation …

Immune checkpoint inhibitors (ICIs) are a novel class of immunotherapy drugs that have
improved the treatment of a broad spectrum of cancers as metastatic melanoma, non-small …

The first human orthotopic liver transplantation (LT) in Europe was performed by Sir Roy
Calne in Cambridge in 1968 [1], only one year after the first successful human liver …

Post-Transplantation Lymphoproliferative Disorders Solid-organ and hematopoietic stem-
cell transplants are widely used for various life-threatening medical disorders. Prophylaxis …

Head and neck squamous cell carcinomas (HNSCCs) are highly aggressive, multi-factorial
tumors in the upper aerodigestive tract affecting more than half a million patients worldwide …

Successful solid organ transplantation reflects meticulous attention to the details of
immunosuppression, balancing risks for graft rejection against risks for infection. The “net …

Abstract Background Checkpoint inhibitors (CPIs) have revolutionized the treatment of
cancer, but their use remains limited by off-target inflammatory and immune-related adverse …

Available evidence suggests that the incidence of leukemia and lymphoma tends to be
higher in highly developed regions of the world and among Whites in the United States …

Highlights•Solid organ transplantation (SOT) patients or patients with active ADs have been
largely excluded from ICIs clinical trials because of the risk of allograft rejection or severe …