Consensus guidelines for therapeutic drug monitoring in neuropsychopharmacology: update 2017
C Hiemke, N Bergemann, HW Clement… - …, 2018 - thieme-connect.com
Therapeutic drug monitoring (TDM) is the quantification and interpretation of drug
concentrations in blood to optimize pharmacotherapy. It considers the interindividual …
concentrations in blood to optimize pharmacotherapy. It considers the interindividual …
A Review of the Important Role of CYP2D6 in Pharmacogenomics
C Taylor, I Crosby, V Yip, P Maguire, M Pirmohamed… - Genes, 2020 - mdpi.com
Cytochrome P450 2D6 (CYP2D6) is a critical pharmacogene involved in the metabolism of~
20% of commonly used drugs across a broad spectrum of medical disciplines including …
20% of commonly used drugs across a broad spectrum of medical disciplines including …
Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders
Objectives: To provide guidance for the management of mood disorders, based on scientific
evidence supplemented by expert clinical consensus and formulate recommendations to …
evidence supplemented by expert clinical consensus and formulate recommendations to …
Prediction of CYP2D6 phenotype from genotype across world populations
A Gaedigk, K Sangkuhl, M Whirl-Carrillo, T Klein… - Genetics in …, 2017 - nature.com
Purpose: Owing to its highly polymorphic nature and major contribution to the metabolism
and bioactivation of numerous clinically used drugs, CYP2D6 is one of the most extensively …
and bioactivation of numerous clinically used drugs, CYP2D6 is one of the most extensively …
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP2C19 and Voriconazole Therapy
B Moriyama, AO Obeng, J Barbarino… - Clinical …, 2017 - Wiley Online Library
Voriconazole, a triazole antifungal agent, demonstrates wide interpatient variability in serum
concentrations, due in part to variant CYP2C19 alleles. Individuals who are CYP2C19 …
concentrations, due in part to variant CYP2C19 alleles. Individuals who are CYP2C19 …
Implementing pharmacogenomics in Europe: design and implementation strategy of the ubiquitous pharmacogenomics consortium
CH van der Wouden… - Clinical …, 2017 - Wiley Online Library
Despite scientific and clinical advances in the field of pharmacogenomics (PGx), application
into routine care remains limited. Opportunely, several implementation studies and …
into routine care remains limited. Opportunely, several implementation studies and …
Preemptive clinical pharmacogenetics implementation: current programs in five US medical centers
HM Dunnenberger, KR Crews… - Annual review of …, 2015 - annualreviews.org
Although the field of pharmacogenetics has existed for decades, practioners have been slow
to implement pharmacogenetic testing in clinical care. Numerous publications describe the …
to implement pharmacogenetic testing in clinical care. Numerous publications describe the …
[HTML][HTML] Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development …
Abstract The Clinical Pharmacogenetics Implementation Consortium (CPIC) publishes
genotype-based drug guidelines to help clinicians understand how available genetic test …
genotype-based drug guidelines to help clinicians understand how available genetic test …
Comparison of the guidelines of the clinical pharmacogenetics implementation consortium and the dutch pharmacogenetics working group
PCD Bank, KE Caudle, JJ Swen… - Clinical …, 2018 - Wiley Online Library
Both the Clinical Pharmacogenetics Implementation Consortium (CPIC) and Dutch
Pharmacogenetics Working Group provide therapeutic recommendations for well‐known …
Pharmacogenetics Working Group provide therapeutic recommendations for well‐known …
Psychopharmacological treatment of obsessive-compulsive disorder (OCD)
A Del Casale, S Sorice, A Padovano… - Current …, 2019 - ingentaconnect.com
Background: Obsessive-compulsive disorder (OCD) is associated with affective and
cognitive symptoms causing personal distress and reduced global functioning. These have …
cognitive symptoms causing personal distress and reduced global functioning. These have …