[HTML][HTML] The mechanisms of pharmacokinetic food-drug interactions–A perspective from the UNGAP group

M Koziolek, S Alcaro, P Augustijns, AW Basit… - European Journal of …, 2019 - Elsevier
The simultaneous intake of food and drugs can have a strong impact on drug release,
absorption, distribution, metabolism and/or elimination and consequently, on the efficacy …

Nutrimetabolomics: an integrative action for metabolomic analyses in human nutritional studies

MM Ulaszewska, CH Weinert… - Molecular nutrition & …, 2019 - Wiley Online Library
The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

[PDF][PDF] Flavonoids and phenolic acids: Role and biochemical activity in plants and human

A Ghasemzadeh, N Ghasemzadeh - J. Med. Plants Res, 2011 - researchgate.net
Flavonoids and phenolic acids make up one of the most pervasive groups of plant
phenolics. Due to their importance in plants and human health, it would be useful to have a …

Prediction of solubility and permeability class membership: provisional BCS classification of the world's top oral drugs

A Dahan, JM Miller, GL Amidon - The AAPS journal, 2009 - Springer
Abstract The Biopharmaceutics Classification System (BCS) categorizes drugs into one of
four biopharmaceutical classes according to their water solubility and membrane …

Polyphenols as dietary supplements: A double-edged sword

KR Martin, CL Appel - Nutrition and Dietary Supplements, 2009 - Taylor & Francis
Increased consumption of fruits and vegetables is associated with a lower risk of chronic
disease such as cardiovascular disease, some forms of cancer, and neurodegeneration. Pro …

Overview of metabolism and bioavailability enhancement of polyphenols

U Lewandowska, K Szewczyk, E Hrabec… - Journal of agricultural …, 2013 - ACS Publications
A proper diet is one of major factors contributing to good health and is directly related to
general condition of the organism. Phenolic compounds are abundant in foods and …

Discovery and characterization of potent dual P-glycoprotein and CYP3A4 inhibitors: design, synthesis, cryo-EM analysis, and biological evaluations

S Urgaonkar, K Nosol, AM Said… - Journal of Medicinal …, 2021 - ACS Publications
Targeted concurrent inhibition of intestinal drug efflux transporter P-glycoprotein (P-gp) and
drug metabolizing enzyme cytochrome P450 3A4 (CYP3A4) is a promising approach to …

Fruit juice inhibition of uptake transport: a new type of food–drug interaction

DG Bailey - British journal of clinical pharmacology, 2010 - Wiley Online Library
A new type of interaction in which fruit juices diminish oral drug bioavailability through
inhibition of uptake transport is the focus of this review. The discovery was based on an …

An assessment of statin safety by muscle experts

PD Thompson, PM Clarkson, RS Rosenson - The American journal of …, 2006 - Elsevier
The National Lipid Association's (NLA) Muscle Safety Expert Panel was charged with the
duty of examining the definitions, causative factors, and management of statin myopathy …

Diet and psoriasis: experimental data and clinical evidence

M Wolters - British Journal of Dermatology, 2005 - academic.oup.com
Psoriasis is considered as a T‐cell‐mediated inflammatory skin disease which is
characterized by hyperproliferation and poor differentiation of epidermal keratinocytes …