▪ Abstract Environmental and hormonal regulators of diapause have been reasonably well
defined, but our understanding of the molecular regulation of diapause remains in its …

David Keilin (Proc. Roy. Soc. Lond. B, 150, 1959, 149–191) coined the term
'cryptobiosis'(hidden life) and defined it as 'the state of an organism when it shows no visible …

Small heat shock proteins (sHSPs) associate with nuclei, cytoskeleton and membranes, and
as molecular chaperones they bind partially denatured proteins, thereby preventing …

Water is critical for the survival of most cells and organisms. Remarkably, a small number of
multicellular animals are able to survive nearly complete drying. The phenomenon of …

Trehalose is a disaccharide of glucose that is found at high concentrations in a wide variety
of organisms that naturally survive drying in nature. Many years ago we reported that this …

Diapause entails molecular, physiological and morphological remodeling of living animals,
culminating in a dormant state characterized by enhanced stress tolerance. Molecular …

To withstand desiccation, many invertebrates such as rotifers, nematodes and tardigrades
enter a state known as anhydrobiosis, which is thought to require accumulation of …

Small heat shock/α-crystallin proteins are defined by a conserved sequence of
approximately 90 amino acid residues, termed the α-crystallin domain, which is bounded by …

Abstract The Center for Biostabilization at UC Davis is attempting to stabilize mammalian
cells in the dry state. We review here some of the lessons from nature that we have been …

Small heat shock proteins (sHSPs) are chaperones with well-characterized roles in heat
stress, but potential roles for sHSPs in desiccation tolerance have not been as thoroughly …