Maximizing safe resection of low-and high-grade glioma

SL Hervey-Jumper, MS Berger - Journal of neuro-oncology, 2016 - Springer
Surgical resection plays a central role in the management of gliomas. In this study, we
review the evidence in support of extent of resection to improve survival, symptom …

[HTML][HTML] Cognitive impairment associated with cancer: a brief review

JC Pendergrass, SD Targum… - Innovations in clinical …, 2018 - ncbi.nlm.nih.gov
This brief review explores the areas of cognitive impairment that have been observed in
cancer patients and survivors, the cognitive assessment tools used, and the management of …

Postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease (NCCTG N107C/CEC· 3): a multicentre …

PD Brown, KV Ballman, JH Cerhan… - The Lancet …, 2017 - thelancet.com
Background Whole brain radiotherapy (WBRT) is the standard of care to improve intracranial
control following resection of brain metastasis. However, stereotactic radiosurgery (SRS) to …

Effect of radiosurgery alone vs radiosurgery with whole brain radiation therapy on cognitive function in patients with 1 to 3 brain metastases: a randomized clinical trial

PD Brown, K Jaeckle, KV Ballman, E Farace… - Jama, 2016 - jamanetwork.com
Importance Whole brain radiotherapy (WBRT) significantly improves tumor control in the
brain after stereotactic radiosurgery (SRS), yet because of its association with cognitive …

Establishing percent resection and residual volume thresholds affecting survival and recurrence for patients with newly diagnosed intracranial glioblastoma

KL Chaichana, I Jusue-Torres… - Neuro …, 2014 - academic.oup.com
Introduction Surgery is first-line therapy for glioblastoma, and there is evidence that gross
total resection is associated with improved survival. Gross total resection, however, is not …

[HTML][HTML] Quality of life data as prognostic indicators of survival in cancer patients: an overview of the literature from 1982 to 2008

A Montazeri - Health and quality of life outcomes, 2009 - Springer
Background Health-related quality of life and survival are two important outcome measures
in cancer research and practice. The aim of this paper is to examine the relationship …

[PDF][PDF] The prognostic significance of patient-reported outcomes in cancer clinical trials

CC Gotay, CT Kawamoto, A Bottomley… - Journal of clinical …, 2008 - researchgate.net
Purpose Patient-reported outcomes (PROs), routinely collected as a part of cancer clinical
trials, have been linked with survival in numerous clinical studies, but a comprehensive …

Association of surgically acquired motor and language deficits on overall survival after resection of glioblastoma multiforme

MJ McGirt, D Mukherjee, KL Chaichana, KD Than… - …, 2009 - journals.lww.com
OBJECTIVE Balancing the benefits of extensive tumor resection with the consequence of
potential postoperative deficits remains a challenge in malignant astrocytoma surgery …

Nomograms for predicting survival of patients with newly diagnosed glioblastoma: prognostic factor analysis of EORTC and NCIC trial 26981-22981/CE. 3

T Gorlia, MJ van den Bent, ME Hegi… - The lancet …, 2008 - thelancet.com
Background A randomised trial published by the European Organisation for Research and
Treatment of Cancer (EORTC) and the National Cancer Institute of Canada (NCIC) Clinical …

Health-related quality of life and cancer clinical trials

D Osoba - Therapeutic advances in medical oncology, 2011 - journals.sagepub.com
The measurement of patient-reported outcomes, including health-related quality of life, is a
new initiative which has emerged and grown over the past four decades. Following the …