[HTML][HTML] Candidate glaucoma biomarkers: from proteins to metabolites, and the pitfalls to clinical applications

AFV Cueto, L Álvarez, M García, A Álvarez-Barrios… - Biology, 2021 - mdpi.com
Simple Summary Glaucoma is a devastating eye disease causing progressive vision loss
and consequent irreversible blindness. The global prevalence of glaucoma is estimated at …

ANPELA: analysis and performance assessment of the label-free quantification workflow for metaproteomic studies

J Tang, J Fu, Y Wang, B Li, Y Li, Q Yang… - Briefings in …, 2020 - academic.oup.com
Label-free quantification (LFQ) with a specific and sequentially integrated workflow of
acquisition technique, quantification tool and processing method has emerged as the …

[HTML][HTML] The aqueous humor proteome of primary open angle glaucoma: an extensive review

WHG Hubens, RJC Mohren, I Liesenborghs… - Experimental Eye …, 2020 - Elsevier
Background We reviewed the literature on the aqueous humor (AH) proteome of primary
open angle glaucoma (POAG) patients in order to obtain deeper insight into the …

[HTML][HTML] Oxidative stress induced dysfunction of protein synthesis in 661w mice photoreceptor cells

L Deng, V Gupta, M Abyadeh, N Chitranshi… - Proteomes, 2023 - mdpi.com
Photoreceptor cells are highly susceptible to oxidative-stress-induced damage due to their
high metabolic rate. Oxidative stress plays a key role in driving pathological events in …

Insights into the regulatory molecules involved in glaucoma pathogenesis

H Moazzeni, M Khani, E Elahi - American Journal of Medical …, 2020 - Wiley Online Library
Glaucoma is an important cause of irreversible blindness, characterized by optic nerve
anomalies. Increased intraocular pressure (IOP) and aging are major risk factors. Retinal …

Low expression of GSTP1 in the aqueous humour of patients with primary open‐angle glaucoma

A Liu, L Wang, Q Feng, D Zhang… - Journal of Cellular …, 2021 - Wiley Online Library
Primary open‐angle glaucoma (POAG) is characterized by irreversible neurodegeneration
accompanied by visual field defects and high intraocular pressure. Currently, an effective …

[HTML][HTML] Proteome alterations in aqueous humour of primary open angle glaucoma patients

H Liu, F Anders, S Funke, K Mercieca… - International Journal …, 2020 - ncbi.nlm.nih.gov
AIM To unravel the primary open angle glaucoma (POAG) related proteomic changes in
aqueous humour (AH). METHODS Totally 35 patients listed for cataract surgery (controls: n …

Potential Immune-Inflammatory Proteome Biomarkers for Guiding the Treatment of Patients with Primary Acute Angle-Closure Glaucoma Caused by COVID-19

Q Gong, M Fu, J Wang, S Zhao… - Journal of Proteome …, 2024 - ACS Publications
Primary acute angle-closure glaucoma (PAACG) is a sight-threatening condition that can
lead to blindness. With the increasing incidence of COVID-19, a multitude of people are …

[HTML][HTML] Proteome characterization of glaucoma aqueous humor

X Liu, X Liu, Y Wang, H Sun, Z Guo, X Tang, J Li… - Molecular & Cellular …, 2021 - ASBMB
Glaucoma is the leading cause of irreversible blindness worldwide. The proteome
characterization of glaucoma is not clearly understood. A total of 175 subjects, including 57 …

Detection of proteins associated with extracellular matrix regulation in the aqueous humour of patients with primary glaucoma

S Nikhalashree, R George, B Shantha… - Current eye …, 2019 - Taylor & Francis
Purpose The protein composition of aqueous humour (AH) has held significant relevance
and remains to be the prime sample in the discovery of biomarkers in glaucoma. The …