[HTML][HTML] Angiogenesis in hepatocellular carcinoma: mechanisms and anti-angiogenic therapies

C Yao, S Wu, J Kong, Y Sun, Y Bai, R Zhu… - Cancer Biology & …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-associated death
worldwide. Angiogenesis, the process of formation of new blood vessels, is required for …

Vascular normalization: reshaping the tumor microenvironment and augmenting antitumor immunity for ovarian cancer

P Yu, Y Wang, D Yuan, Y Sun, S Qin, T Li - Frontiers in Immunology, 2023 - frontiersin.org
Ovarian cancer remains a challenging disease with limited treatment options and poor
prognosis. The tumor microenvironment (TME) plays a crucial role in tumor growth …

Pathogenesis and function of interleukin-35 in rheumatoid arthritis

PL Xin, LF Jie, Q Cheng, DY Bin… - Frontiers in Pharmacology, 2021 - frontiersin.org
It is well known that RA (Rheumatoid arthritis) is an autoimmune disease characterized by
multiple and symmetric arthropathy. The main pathological features of RA are synovial …

[HTML][HTML] The mechanisms of renin–angiotensin system in hepatocellular carcinoma: From the perspective of liver fibrosis, HCC cell proliferation, metastasis and …

HF Zhang, X Gao, X Wang, X Chen, Y Huang… - Biomedicine & …, 2021 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, of which
the occurrence and development involve a variety of pathophysiological processes, such as …

Macrotrabecular-Massive Hepatocellular Carcinoma: What Should We Know?

X Li, Q Yao, C Liu, J Wang, H Zhang… - Journal of …, 2022 - Taylor & Francis
Hepatocellular carcinoma is one of the most common malignancies globally. Recently, a
newly identified histological subtype, designated as “macrotrabecular-massive …

A five-gene-based prognostic signature for hepatocellular carcinoma

D Tian, Y Yu, L Zhang, J Sun, W Jiang - Frontiers in Medicine, 2021 - frontiersin.org
Objective: This study intends to identify potential prognostic marker genes associated with
the prognosis of patients suffering from hepatocellular carcinoma (HCC) based on TCGA …

Angiopoietin-2 and the Vascular Endothelial Growth Factor Promote Migration and Invasion in Hepatocellular Carcinoma-and Intrahepatic Cholangiocarcinoma …

A Romanzi, F Milosa, G Marcelli, RM Critelli, S Lasagni… - Biomedicines, 2023 - mdpi.com
Aggressive hepatocellular carcinoma (HCC) overexpressing Angiopoietin-2 (ANG-2)(a
protein linked with angiogenesis, proliferation, and epithelial–mesenchymal transition …

Changes in serum growth factors during lenvatinib predict the post progressive survival in patients with unresectable hepatocellular carcinoma

Z Yang, G Suda, O Maehara, M Ohara, S Yoshida… - Cancers, 2022 - mdpi.com
Simple Summary In this study, we firstly revealed that the pattern of developing resistance to
lenvatinib varies and determines the prognosis of patients with unresectable hepatocellular …

[HTML][HTML] Upregulation of MAD2L1 mediated by ncRNA axis is associated with poor prognosis and tumor immune infiltration in hepatocellular carcinoma: A review

S Liu, M Miao, L Kang - Medicine, 2023 - journals.lww.com
Background: The mortality rate and prognosis of patients with hepatocellular carcinoma
(HCC) are well known. A variety of highly malignant human cancers express mitotic arrest …

USP11 promotes glycolysis by regulating HIF‐1α stability in hepatocellular carcinoma

L Qiao, W Hu, L Li, X Chen, L Liu… - Journal of Cellular and …, 2024 - Wiley Online Library
Understanding the mechanisms underlying metastasis in hepatocellular carcinoma (HCC) is
crucial for developing new therapies against this fatal disease. Deubiquitinase ubiquitin …