Vitamin C as an antioxidant: evaluation of its role in disease prevention
SJ Padayatty, A Katz, Y Wang, P Eck… - Journal of the …, 2003 - Taylor & Francis
Vitamin C in humans must be ingested for survival. Vitamin C is an electron donor, and this
property accounts for all its known functions. As an electron donor, vitamin C is a potent …
property accounts for all its known functions. As an electron donor, vitamin C is a potent …
Does vitamin C act as a pro‐oxidant under physiological conditions?
Vitamin C readily scavenges reactive oxygen and nitrogen species and may thereby prevent
oxidative damage to important biological macromolecules such as DNA, lipids, and proteins …
oxidative damage to important biological macromolecules such as DNA, lipids, and proteins …
Biological and environmental transformations of copper-based nanomaterials
Z Wang, A Von Dem Bussche, PK Kabadi, AB Kane… - ACS …, 2013 - ACS Publications
Copper-based nanoparticles are an important class of materials with applications as
catalysts, conductive inks, and antimicrobial agents. Environmental and safety issues are …
catalysts, conductive inks, and antimicrobial agents. Environmental and safety issues are …
The Pseudomonas Quinolone Signal (PQS) Balances Life and Death in Pseudomonas aeruginosa Populations
S Häussler, T Becker - PLoS pathogens, 2008 - journals.plos.org
When environmental conditions deteriorate and become inhospitable, generic survival
strategies for populations of bacteria may be to enter a dormant state that slows down …
strategies for populations of bacteria may be to enter a dormant state that slows down …
Induction of oxidative DNA damage by carcinogenic metals
W Bal, KS Kasprzak - Toxicology letters, 2002 - Elsevier
The metal ions carcinogenic to humans are As, Be, Cd, Cr and Ni, and the candidates also
include Co, Cu, Fe and Pt. A range of molecular mechanisms was proposed for these …
include Co, Cu, Fe and Pt. A range of molecular mechanisms was proposed for these …
An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice
A Mansouri, I Gaou, C de Kerguenec, S Amsellem… - Gastroenterology, 1999 - Elsevier
Background & Aims: Ethanol causes oxidative stress in the hepatic mitochondria of
experimental animals and mitochondrial DNA deletions in alcoholics. We postulated that …
experimental animals and mitochondrial DNA deletions in alcoholics. We postulated that …
Review of copper and copper alloys as immune and antibacterial element
Y Wang, H LI, X Yuan, Y Jiang, Z Xiao… - Transactions of Nonferrous …, 2022 - Elsevier
This review discussed the relationship among copper, human, and bacteria. Copper plays
an important role in human immunity. Copper can boost human immune defense reactions …
an important role in human immunity. Copper can boost human immune defense reactions …
Quantitation of 8-oxoguanine and strand breaks produced by four oxidizing agents
LJ Kennedy, K Moore, JL Caulfield… - Chemical research in …, 1997 - ACS Publications
Reactive oxygen species, produced endogenously or by exposure to environmental
chemicals and ionizing radiation, induce a wide range of DNA lesions. The variety of …
chemicals and ionizing radiation, induce a wide range of DNA lesions. The variety of …
Oxidative DNA damage induced by copper and hydrogen peroxide promotes CG→ TT tandem mutations at methylated CpG dinucleotides in nucleotide excision …
DH Lee, TR O'Connor, GP Pfeifer - Nucleic acids research, 2002 - academic.oup.com
Oxidative DNA damage may play an important role in human disease including cancer.
Previously, mutational spectra have been determined using systems that include transition …
Previously, mutational spectra have been determined using systems that include transition …
Production of DNA Strand Breaks in Vitro and Reactive Oxygen Species in Vitro and in HL-60 Cells by PCB Metabolites
A Srinivasan, HJ Lehmler, LW Robertson… - Toxicological …, 2001 - academic.oup.com
PCBs are industrial chemicals that continue to contaminate our environment. They cause
various toxic effects in animals and in exposed human populations. The mechanisms of …
various toxic effects in animals and in exposed human populations. The mechanisms of …