Communities eating a western-like diet, rich in fat, sugar and significantly deprived of fibers,
share a relevant increased risk of both metabolic and cancerous diseases. Even more …

This article focuses on discoveries of the mechanisms governing the regulation of
glycerolipid metabolism and stress response signaling in response to the phospholipid …

S-adenosylmethionine (SAM) is the methyl donor for biological methylation modifications
that regulate protein and nucleic acid functions. Here, we show that methylation of a …

Mitochondria generate ATP and play regulatory roles in various cellular activities. Cancer
cells often exhibit fragmented mitochondria. However, the underlying mechanism remains …

Inositol phosphates (IPs) comprise a network of phosphorylated molecules that play multiple
signaling roles in eukaryotes. IPs synthesis is believed to originate with IP3 generated from …

Abstract myo-Inositol-1-phosphate synthase (MIPS) catalyzes the limiting step of inositol
biosynthesis and has crucial roles in plant growth and development. In response to stress …

Background Glucaric acid is a high-value-added chemical that can be used in various fields.
Because chemical oxidation of glucose to produce glucaric acid is not environmentally …

Inositol pyrophosphates are water soluble derivatives of inositol that contain pyrophosphate
or diphosphate moieties in addition to monophosphates. The best characterised inositol …

Inositol plays a significant role in cellular function and signaling. Studies in yeast have
demonstrated an “inositol-less death” phenotype, suggesting that inositol is an essential …

Recent research further clarified the molecular mechanisms that link nutrient signaling and
pH homeostasis with the regulation of growth and survival of the budding yeast …