Hypertension, the renin–angiotensin system, and the risk of lower respiratory tract infections and lung injury: implications for COVID-19: European Society of …
Systemic arterial hypertension (referred to as hypertension herein) is a major risk factor of
mortality worldwide, and its importance is further emphasized in the context of the novel …
mortality worldwide, and its importance is further emphasized in the context of the novel …
Vascular inflammation and oxidative stress: major triggers for cardiovascular disease
S Steven, K Frenis, M Oelze, S Kalinovic… - Oxidative medicine …, 2019 - Wiley Online Library
Cardiovascular disease is a leading cause of death and reduced quality of life, proven by
the latest data of the Global Burden of Disease Study, and is only gaining in prevalence …
the latest data of the Global Burden of Disease Study, and is only gaining in prevalence …
Angiotensin II signal transduction: an update on mechanisms of physiology and pathophysiology
The renin-angiotensin-aldosterone system plays crucial roles in cardiovascular physiology
and pathophysiology. However, many of the signaling mechanisms have been unclear. The …
and pathophysiology. However, many of the signaling mechanisms have been unclear. The …
Immune mechanisms of hypertension
GR Drummond, A Vinh, TJ Guzik… - Nature Reviews …, 2019 - nature.com
Hypertension affects 30% of adults and is the leading risk factor for heart attack and stroke.
Traditionally, hypertension has been regarded as a disorder of two systems that are involved …
Traditionally, hypertension has been regarded as a disorder of two systems that are involved …
[HTML][HTML] Role of inflammation, immunity, and oxidative stress in hypertension: New insights and potential therapeutic targets
Z Zhang, L Zhao, X Zhou, X Meng, X Zhou - Frontiers in Immunology, 2023 - frontiersin.org
Hypertension is regarded as the most prominent risk factor for cardiovascular diseases,
which have become a primary cause of death, and recent research has demonstrated that …
which have become a primary cause of death, and recent research has demonstrated that …
Oxidative stress, inflammation, and vascular aging in hypertension
TJ Guzik, RM Touyz - Hypertension, 2017 - Am Heart Assoc
Guzik and Touyz Oxidation and Inflammation in Vascular Aging 661 and endothelium. 22
Perivascular fibrosis is greatly dependent on immune cells because it is prevented in …
Perivascular fibrosis is greatly dependent on immune cells because it is prevented in …
Hypertension: do inflammation and immunity hold the key to solving this epidemic?
Elevated cardiovascular risk including stroke, heart failure, and heart attack is present even
after normalization of blood pressure in patients with hypertension. Underlying immune cell …
after normalization of blood pressure in patients with hypertension. Underlying immune cell …
Imbalance of gut microbiome and intestinal epithelial barrier dysfunction in patients with high blood pressure
Recent evidence indicates a link between gut pathology and microbiome with hypertension
(HTN) in animal models. However, whether this association exists in humans is unknown …
(HTN) in animal models. However, whether this association exists in humans is unknown …
Mitochondrial deacetylase Sirt3 reduces vascular dysfunction and hypertension while Sirt3 depletion in essential hypertension is linked to vascular inflammation and …
Rationale: Hypertension represents a major risk factor for stroke, myocardial infarction, and
heart failure and affects 30% of the adult population. Mitochondrial dysfunction contributes to …
heart failure and affects 30% of the adult population. Mitochondrial dysfunction contributes to …
Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal …
M Czesnikiewicz-Guzik, G Osmenda… - European heart …, 2019 - academic.oup.com
Aims Inflammation is an important driver of hypertension. Periodontitis is a chronic
inflammatory disease, which could provide a mechanism for pro-hypertensive immune …
inflammatory disease, which could provide a mechanism for pro-hypertensive immune …