Plants and Plant‐Derived Molecules as Natural Immunomodulators
Background. Nowadays, the immunomodulatory properties of plants have been studied
extensively with greater interest due to increasing awareness and combating the severity of …
extensively with greater interest due to increasing awareness and combating the severity of …
[HTML][HTML] Health-related quality of life in primary immunodeficiencies: impact of delayed diagnosis and treatment burden
Accurate and timely diagnosis of primary immunodeficiencies (PID) is an ongoing effort.
Individuals with PID can be severely impacted by their disease and many experience …
Individuals with PID can be severely impacted by their disease and many experience …
Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations
J Thalhammer, G Kindle, A Nieters, S Rusch… - Journal of Allergy and …, 2021 - Elsevier
Background Inborn errors of immunity (IEI) are rare diseases, which makes diagnosis a
challenge. A better description of the initial presenting manifestations should improve …
challenge. A better description of the initial presenting manifestations should improve …
[HTML][HTML] Growth in diagnosis and treatment of primary immunodeficiency within the global Jeffrey Modell Centers Network
J Quinn, V Modell, JS Orange, F Modell - Allergy, Asthma & Clinical …, 2022 - Springer
Background Primary immunodeficiencies (PI), which include more than 450 single-gene
inborn errors of immunity and may affect up to 1% of the population, are genetic disorders …
inborn errors of immunity and may affect up to 1% of the population, are genetic disorders …
[HTML][HTML] Consensus Middle East and North Africa Registry on inborn errors of immunity
Background Inborn errors of immunity (IEIs) are a heterogeneous group of genetic defects of
immunity, which cause high rates of morbidity and mortality mainly among children due to …
immunity, which cause high rates of morbidity and mortality mainly among children due to …
[HTML][HTML] Genetic and immunologic evaluation of children with inborn errors of immunity and severe or critical COVID-19
Background Most severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected
individuals are asymptomatic or only exhibit mild disease. In about 10% of cases, the …
individuals are asymptomatic or only exhibit mild disease. In about 10% of cases, the …
[HTML][HTML] The PID principles of care: where are we now? A global status report based on the PID life index
J Nordin, L Solís, J Prévot, N Mahlaoui… - Frontiers in …, 2021 - frontiersin.org
A global gold standard framework for primary immunodeficiency (PID) care, structured
around six principles, was published in 2014. To measure the implementation status of …
around six principles, was published in 2014. To measure the implementation status of …
SARS-CoV-2 infection and response to COVID-19 vaccination in patients with primary immunodeficiencies
R Paris - The Journal of Infectious Diseases, 2023 - academic.oup.com
Primary immunodeficiencies (PIDs) are heterogeneous, rare disorders that increase
susceptibility to infection and/or immune dysregulation. Individuals with certain PIDs are at …
susceptibility to infection and/or immune dysregulation. Individuals with certain PIDs are at …
[HTML][HTML] Expanding horizons in complement analysis and quality control
A Frazer-Abel, M Kirschfink, Z Prohászka - Frontiers in immunology, 2021 - frontiersin.org
Complement not only plays a key role in host microbial defense but also modulates the
adaptive immune response through modification of T-and B-cell reactivity. Moreover, a …
adaptive immune response through modification of T-and B-cell reactivity. Moreover, a …
Improving access to therapy for patients with inborn errors of immunity: a call to action
MJ Dorsey, A Condino-Neto - The Journal of Allergy and Clinical …, 2023 - Elsevier
Breakthroughs in sequencing technology, targeted immunotherapy, and immune
reconstituting treatment have increased the pool of patients with inborn errors of immunity …
reconstituting treatment have increased the pool of patients with inborn errors of immunity …