Of chloroquine and COVID-19

F Touret, X de Lamballerie - Antiviral research, 2020 - Elsevier
Recent publications have brought attention to the possible benefit of chloroquine, a broadly
used antimalarial drug, in the treatment of patients infected by the novel emerged …

SARS-CoV-2/COVID-19: viral genomics, epidemiology, vaccines, and therapeutic interventions

M Uddin, F Mustafa, TA Rizvi, T Loney, H Al Suwaidi… - Viruses, 2020 - mdpi.com
The COVID-19 pandemic is due to infection caused by the novel SARS-CoV-2 virus that
impacts the lower respiratory tract. The spectrum of symptoms ranges from asymptomatic …

In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS …

X Yao, F Ye, M Zhang, C Cui, B Huang… - Clinical infectious …, 2020 - academic.oup.com
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first broke
out in 2019 and subsequently spread worldwide. Chloroquine has been sporadically used …

Chloroquine and hydroxychloroquine in covid-19

RE Ferner, JK Aronson - Bmj, 2020 - bmj.com
TheBMJ in 1925 cautiously endorsed Moellgaard's gold treatment for tuberculosis, 1
although it found his pharmacological reasoning “both interesting and instructive.” 2 We …

Drug repositioning: Progress and challenges in drug discovery for various diseases

Y Hua, X Dai, Y Xu, G Xing, H Liu, T Lu, Y Chen… - European Journal of …, 2022 - Elsevier
Compared with traditional de novo drug discovery, drug repurposing has become an
attractive drug discovery strategy due to its low-cost and high efficiency. Through a …

Biochemistry and molecular biology of flaviviruses

NJ Barrows, RK Campos, KC Liao, KR Prasanth… - Chemical …, 2018 - ACS Publications
Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile,
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …

A broad-spectrum virus-and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2

H Zhao, KKW To, KH Sze, TTM Yung, M Bian… - Nature …, 2020 - nature.com
The 2019 novel respiratory virus (SARS-CoV-2) causes COVID-19 with rapid global
socioeconomic disruptions and disease burden to healthcare. The COVID-19 and previous …

[HTML][HTML] Therapeutic use of chloroquine and hydroxychloroquine in COVID-19 and other viral infections: A narrative review

AM Hashem, BS Alghamdi, AA Algaissi… - Travel medicine and …, 2020 - Elsevier
Abstract The rapidly spreading Coronavirus Disease (COVID-19) pandemic, caused by the
severe acute respiratory syndrome coronavirus (SARS-CoV-2), represents an …

[HTML][HTML] COVID-19: an update on diagnostic and therapeutic approaches

M Iyer, K Jayaramayya, MD Subramaniam, SB Lee… - BMB …, 2020 - ncbi.nlm.nih.gov
The unexpected pandemic set off by the novel coronavirus 2019 (COVID-19) has caused
severe panic among people worldwide. COVID-19 has created havoc, and scientists and …

An update on antiviral therapy against SARS-CoV-2: how far have we come?

O Indari, S Jakhmola, E Manivannan… - Frontiers in …, 2021 - frontiersin.org
COVID-19 pandemic has spread worldwide at an exponential rate affecting millions of
people instantaneously. Currently, various drugs are under investigation to treat an …