The mammalian cerebral cortex represents one of the most recent and astonishing
inventions of nature, responsible of a large diversity of functions that range from sensory …

During embryonic development, the cardiovascular system and the central nervous system
exhibit a coordinated developmental process through intricate interactions. Congenital heart …

Retrotransposons are mobile DNA sequences duplicated via transcription and reverse
transcription of an RNA intermediate. Cis-regulatory elements encoded by retrotransposons …

Determining the causes of schizophrenia has been a notoriously intractable problem,
resistant to a multitude of investigative approaches over centuries. In recent decades …

Aim This study mapped the spatiotemporal positions and connectivity of Onecut3+ neuronal
populations in the developing and adult mouse brain. Methods We generated fluorescent …

Advancements in molecular biology have revolutionized our understanding of complex
diseases, with Alzheimer's disease being a prime example. Single-cell sequencing …

Infection during pregnancy is a substantial risk factor for the unborn child to develop autism
or schizophrenia later in life, and is thought to be driven by maternal immune activation …

Neuronal differentiation is regulated by neuronal activity. Here, we analyzed dendritic and
axonal growth of Basket cells (BCs) and non-Basket cells (non-BCs) using sparse …

Parvalbumin (PV)-positive GABAergic cells provide robust perisomatic inhibition to
neighboring pyramidal neurons and regulate brain oscillations. Alterations in PV interneuron …

Retrotransposons are a reservoir of cis-regulatory innovation–. Developmental programs
that activate these elements could, in principle, manifest in lineage-specific …