Enriched circulating and tumor-resident TGF-β+ regulatory B cells in patients with melanoma promote FOXP3+ Tregs

RJ Harris, Z Willsmore, R Laddach, S Crescioli… - …, 2022 - Taylor & Francis
ABSTRACT B cells are emerging as key players of anti-tumor adaptive immune responses.
We investigated regulatory and pro-inflammatory cytokine-expressing B cells in patients with …

[HTML][HTML] Nanoliposomal VEGF-R2 peptide vaccine acts as an effective therapeutic vaccine in a murine B16F10 model of melanoma

F Zahedipour, P Zamani, M Mashreghi, M Astaneh… - Cancer …, 2023 - Springer
Background The vascular endothelial growth factor receptor-2 (VEGFR-2) plays an
important role in melanoma development and progression. Peptide vaccines have shown …

[HTML][HTML] Learning from embryogenesis—a comparative expression analysis in melanoblast differentiation and tumorigenesis reveals miRNAs driving melanoma …

L Linck-Paulus, L Lämmerhirt, D Völler… - Journal of clinical …, 2021 - mdpi.com
Malignant melanoma is one of the most dangerous tumor types due to its high metastasis
rates and a steadily increasing incidence. During tumorigenesis, the molecular processes of …

[HTML][HTML] Construction and optimization of multi-platform precision pathways for precision medicine

A Tran, A Wang, J Mickaill, D Strbenac, M Larance… - Scientific Reports, 2024 - nature.com
In the enduring challenge against disease, advancements in medical technology have
empowered clinicians with novel diagnostic platforms. Whilst in some cases, a single test …

[PDF][PDF] New Therapies in Melanoma: Current Trends, Evolving Paradigms, and Future Perspectives

S Shafi, B Challa, AV Parwani, TN Aung - Cutis, 2023 - cdn.mdedge.com
VOL. 112 NO. 5 I NOVEMBER 2023 E33 WWW. MDEDGE. COM/DERMATOLOGY rates and
survival benefit, though efficacy in metastatic patients often is limited by development of …

[PDF][PDF] Quantitative evaluation of network inference methods for single-cell cancer regulomes

C DE VOGELAERE - libstore.ugent.be
In the first place, I would like to thank my promoter Prof. Dr. Ir. Katleen De Preter for allowing
me to conduct research in the translational bioinformatics group at the CMGG and for …