Vitamin K is traditionally connected with blood coagulation, since it is needed for the
posttranslational modification of 7 proteins involved in this cascade. However, it is also …

Intestinal diseases, such as inflammatory bowel diseases (IBDs) and colorectal cancer
(CRC) generally characterized by clinical symptoms, including malabsorption, intestinal …

A hundred years have passed since vitamin E was identified as an essential micronutrient
for mammals. Since then, many biological functions of vitamin E have been unraveled in …

Chronic kidney disease (CKD) patients have a higher risk of developing early
cardiovascular disease (CVD). Although vascular calcification (VC) is one of the strongest …

Chronic Kidney Disease (CKD) patients are at high risk of presenting with arterial
calcification or stiffness, which confers increased cardiovascular mortality and morbidity. In …

Niacin is the precursor to pyridine nucleotides NAD (nicotinamide adenine dinucleotide) and
NADP (nicotinamide adenine dinucleotide phosphate). Niacin (vitamin B 3) is the common …

ABSTRACT A protective role for vitamin K in cardiovascular disease (CVD), a leading cause
of morbidity and mortality, has been proposed because vitamin K–dependent proteins, such …

Background Vitamin K activates matrix Gla protein (MGP), a key inhibitor of vascular
calcification. There is a high prevalence of sub-clinical vitamin K deficiency in patients with …

Vitamin K and vitamin K-dependent proteins have been reported to be associated with a
large spectrum of age-related diseases. While most of these associations have been …

Introduction Vitamin K deficiency among patients on hemodialysis (HD) affects the function
of matrix GLA protein (MGP), a potent vitamin K-dependent inhibitor of vascular calcification …