Inflammatory mechanisms in patients with chronic obstructive pulmonary disease

PJ Barnes - Journal of Allergy and Clinical Immunology, 2016 - Elsevier
Chronic obstructive pulmonary disease (COPD) is associated with chronic inflammation
affecting predominantly the lung parenchyma and peripheral airways that results in largely …

Inflammatory endotypes in COPD

PJ Barnes - Allergy, 2019 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a major global health problem that is
poorly treated by current therapies as it has proved difficult to treat the underlying …

[Translated article] Spanish COPD guidelines (GesEPOC) 2021: Updated pharmacological treatment of stable COPD

M Miravitlles, M Calle, J Molina, P Almagro… - Archivos de …, 2022 - Elsevier
Abstract The Spanish COPD Guidelines (GesEPOC) were first published in 2012, and since
then have undergone a series of updates incorporating new evidence on the diagnosis and …

What is asthma− COPD overlap syndrome? Towards a consensus definition from a round table discussion

DD Sin, M Miravitlles, DM Mannino… - European …, 2016 - Eur Respiratory Soc
Patients with asthma–chronic obstructive pulmonary disease overlap syndrome (ACOS)
have been largely excluded from pivotal therapeutic trials and, as a result, its treatment …

Role of eosinophils in airway inflammation of chronic obstructive pulmonary disease

DP Tashkin, ME Wechsler - International journal of chronic …, 2018 - Taylor & Francis
COPD is a significant cause of morbidity and mortality. In some patients with COPD,
eosinophils contribute to inflammation that promotes airway obstruction; approximately a …

Asthma-COPD overlap syndrome: pathogenesis, clinical features, and therapeutic targets

JM Leung, DD Sin - Bmj, 2017 - bmj.com
Asthma-COPD overlap syndrome (ACOS) or asthma-COPD overlap captures the subset of
patients with airways disease who have features of both asthma and chronic obstructive …

Actualización 2021 de la Guía Española de la EPOC (GesEPOC). Tratamiento farmacológico de la EPOC estable

M Miravitlles, M Calle, J Molina, P Almagro… - Archivos de …, 2022 - Elsevier
Resumen La Guía Española de la Enfermedad Pulmonar Obstructiva Crónica (GesEPOC)
se publicó por primera vez en 2012 y desde entonces ha experimentado una serie de …

Consensus on the asthma–COPD overlap (ACO) between the Spanish COPD guidelines (GesEPOC) and the Spanish guidelines on the management of asthma …

V Plaza, F Álvarez, M Calle, C Casanova… - Archivos de …, 2017 - Elsevier
Following a proposal by the Spanish Society of Pulmonology and Thoracic Surgery
(SEPAR), sponsor of the Spanish COPD Guidelines (GesEPOC) and the Spanish …

[HTML][HTML] Definition and diagnosis of asthma–COPD overlap (ACO)

S Yanagisawa, M Ichinose - Allergology International, 2018 - Elsevier
It is now widely recognized that asthma and COPD can coexist as asthma–COPD overlap
(ACO), but the preliminary attempts at providing universal guidelines for the diagnosis of …

Comorbidome, pattern, and impact of asthma-COPD overlap syndrome in real life

JFM van Boven, M Roman-Rodriguez, JF Palmer… - Chest, 2016 - Elsevier
Background Asthma-COPD overlap syndrome (ACOS) has been described and
acknowledged as a distinct clinical entity; however, its characteristics in daily clinical …