Aptamer-based detection of circulating targets for precision medicine
L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …
Nucleic acid tests for clinical translation
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …
natural biopolymers composed of nucleotides that store, transmit, and express genetic …
DNA walkers for biosensing development
L Song, Y Zhuge, X Zuo, M Li, F Wang - Advanced Science, 2022 - Wiley Online Library
The ability to design nanostructures with arbitrary shapes and controllable motions has
made DNA nanomaterials used widely to construct diverse nanomachines with various …
made DNA nanomaterials used widely to construct diverse nanomachines with various …
Engineering a second‐order DNA logic‐gated nanorobot to sense and release on live cell membranes for multiplexed diagnosis and synergistic therapy
Tumor biomarker‐based theranostics have achieved broad interest and success in recent
years. However, single biomarker‐based recognition can cause false‐positive feedback …
years. However, single biomarker‐based recognition can cause false‐positive feedback …
pH-and miRNA-responsive DNA-tetrahedra/metal–organic framework conjugates: functional sense-and-treat carriers
The synthesis of stimuli-responsive hybrid structures composed of drug-loaded UiO-66
metal–organic framework nanoparticles, NMOFs, locked by DNA tetrahedra gates is …
metal–organic framework nanoparticles, NMOFs, locked by DNA tetrahedra gates is …
From design to applications of stimuli-responsive hydrogel strain sensors
Stimuli-responsive hydrogel strain sensors that synergize the advantages of both soft-wet
hydrogels and smart functional materials have attracted rapidly increasing interest for …
hydrogels and smart functional materials have attracted rapidly increasing interest for …
DNA nanotechnology-empowered nanoscopic imaging of biomolecules
Advances in bioimaging technologies have led to unprecedented findings of novel
biological processes at the nanoscale. However, there remains an ever-lasting demand for …
biological processes at the nanoscale. However, there remains an ever-lasting demand for …
T lymphocyte-captured DNA network for localized immunotherapy
C Yao, C Zhu, J Tang, J Ou, R Zhang… - Journal of the American …, 2021 - ACS Publications
The efficient isolation of immune cells with high purity and low cell damage is important for
immunotherapy and remains highly challenging. We herein report a cell capture DNA …
immunotherapy and remains highly challenging. We herein report a cell capture DNA …
Fluidic multivalent membrane nanointerface enables synergetic enrichment of circulating tumor cells with high efficiency and viability
The ubiquitous biomembrane interface, with its dynamic lateral fluidity, allows membrane-
bound components to rearrange and localize for high-affinity multivalent ligand–receptor …
bound components to rearrange and localize for high-affinity multivalent ligand–receptor …
A framework nucleic acid based robotic nanobee for active targeting therapy
DNA nanotechnology has provided new strategies and platforms for cargo delivery.
However, DNA‐based nanostructures utilized for cargo delivery have mainly focused on …
However, DNA‐based nanostructures utilized for cargo delivery have mainly focused on …