The vaginal microbiome is a well-defined compartment of the human microbiome. It has
unique conditions, characterized by the dominance of one bacterial species, the Lactobacilli …

Gamma-aminobutyric acid (GABA) is widely distributed in nature and considered a potent
bioactive compound with numerous and important physiological functions, such as anti …

The pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-
2) continues to expand. Papain-like protease (PLpro) is one of two SARS-CoV-2 proteases …

Mammalian gut microbiomes profoundly influence host fitness, but the processes that drive
the evolution of host-microbiome systems are poorly understood. Recent studies suggest …

A reverse pH gradient is a hallmark of cancer metabolism, manifested by extracellular
acidosis and intracellular alkalization. While consequences of extracellular acidosis are …

Lactobacillus species are found in nutrient-rich habitats associated with food, feed, plants,
animals and humans. Due to their economic importance, the metabolism, genetics and …

Lactic acid bacteria (LAB) are important starter, commensal, or pathogenic microorganisms.
The stress physiology of LAB has been studied in depth for over 2 decades, fueled mostly by …

Lactobacillus rhamnosus GG (LGG) was the first strain belonging to the genus Lactobacillus
to be patented in 1989 thanks to its ability to survive and to proliferate at gastric acid pH and …

Cancer is a fatal malignancy with high clinical significance and remains one of the major
causes of illness and death. It has no suitable cure existing till now. The safety and stability …

Microbial genome sequencing projects produce numerous sequences of deduced proteins,
only a small fraction of which have been or will ever be studied experimentally. This leaves …