[HTML][HTML] Biosensors for rapid detection of bacterial pathogens in water, food and environment

RC Nnachi, N Sui, B Ke, Z Luo, N Bhalla, D He… - Environment …, 2022 - Elsevier
Conventional techniques (eg, culture-based method) for bacterial detection typically require
a central laboratory and well-trained technicians, which may take several hours or days …

[HTML][HTML] Recent advances in aptamer discovery and applications

Y Zhang, BS Lai, M Juhas - Molecules, 2019 - mdpi.com
Aptamers are short, single-stranded DNA, RNA, or synthetic XNA molecules that can be
developed with high affinity and specificity to interact with any desired targets. They have …

Functional nucleic acid biosensors utilizing rolling circle amplification

RM Bialy, A Mainguy, Y Li, JD Brennan - Chemical Society Reviews, 2022 - pubs.rsc.org
Functional nucleic acids (FNAs), including DNA aptamers and DNAzymes, are finding
increasing use as molecular recognition elements for point-of-care (POC) assays and …

G-quadruplex, Friend or Foe: The Role of the G-quartet in Anticancer Strategies

J Carvalho, JL Mergny, GF Salgado, JA Queiroz… - Trends in molecular …, 2020 - cell.com
The clinical applicability of G-quadruplexes (G4s) as anticancer drugs is currently being
evaluated. Several G4 ligands and aptamers are undergoing clinical trials following the …

Therapeutic applications of AS1411 aptamer, an update review

R Yazdian-Robati, P Bayat, F Oroojalian… - International journal of …, 2020 - Elsevier
Nucleolin or C23, is one of the most abundant non-ribosomal phosphoproteins of nucleolus.
However, in several cancers, nucleolin is highly expressed both intracellularly and on the …

Advances in aptamers, and application of mycotoxins detection: A review

Y Fan, J Li, K Amin, H Yu, H Yang, Z Guo… - Food Research …, 2023 - Elsevier
Mycotoxin contamination in food products can easily cause serious health hazards and
economic losses to human beings. How to accurately detect and effectively control …

Electrochemical biosensors based on nucleic acid aptamers

A Villalonga, AM Pérez-Calabuig… - Analytical and bioanalytical …, 2020 - Springer
During recent decades, nucleic acid aptamers have emerged as powerful biological
recognition elements for electrochemical affinity biosensors. These bioreceptors emulate or …

SELEX: Critical factors and optimization strategies for successful aptamer selection

M Kohlberger, G Gadermaier - Biotechnology and applied …, 2022 - Wiley Online Library
Within the last decade, the application range of aptamers in biochemistry and medicine has
expanded rapidly. More than just a replacement for antibodies, these intrinsically structured …

[HTML][HTML] Methods and applications of in silico aptamer design and modeling

AA Buglak, AV Samokhvalov, AV Zherdev… - International journal of …, 2020 - mdpi.com
Aptamers are nucleic acid analogues of antibodies with high affinity to different targets, such
as cells, viruses, proteins, inorganic materials, and coenzymes. Empirical approaches allow …

Aptasensors versus immunosensors—Which will prevail?

S Arshavsky‐Graham, C Heuer… - Engineering in Life …, 2022 - Wiley Online Library
Since the invention of the first biosensors 70 years ago, they have turned into valuable and
versatile tools for various applications, ranging from disease diagnosis to environmental …