Protein therapeutics: a summary and pharmacological classification

B Leader, QJ Baca, DE Golan - Nature reviews Drug discovery, 2008 - nature.com
Once a rarely used subset of medical treatments, protein therapeutics have increased
dramatically in number and frequency of use since the introduction of the first recombinant …

Acute coronary syndromes: diagnosis and management, part I

A Kumar, CP Cannon - Mayo Clinic Proceedings, 2009 - Elsevier
The term acute coronary syndrome (ACS) refers to any group of clinical symptoms
compatible with acute myocardial ischemia and includes unstable angina (UA), non—ST …

Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council …

HP Adams Jr, G Del Zoppo, MJ Alberts, DL Bhatt… - Stroke, 2007 - Am Heart Assoc
Purpose—Our goal is to provide an overview of the current evidence about components of
the evaluation and treatment of adults with acute ischemic stroke. The intended audience is …

Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation

MS Sabatine, CP Cannon, CM Gibson… - … England Journal of …, 2005 - Mass Medical Soc
Background A substantial proportion of patients receiving fibrinolytic therapy for myocardial
infarction with ST-segment elevation have inadequate reperfusion or reocclusion of the …

Relationship of symptom-onset-to-balloon time and door-to-balloon time with mortality in patients undergoing angioplasty for acute myocardial infarction

CP Cannon, CM Gibson, CT Lambrew, DA Shoultz… - Jama, 2000 - jamanetwork.com
ContextRapid time to treatment with thrombolytic therapy is associated with lower mortality in
patients with acute myocardial infarction (MI). However, data on time to primary angioplasty …

Management of acute myocardial infarction in patients presenting with ST-segment elevation

F Van de Werf, D Ardissino, A Betriu… - European heart …, 2003 - academic.oup.com
The management of acute myocardial infarction continues to undergo major changes. Good
practice should be based on sound evidence derived from well-conducted clinical trials …

Association of hemoglobin levels with clinical outcomes in acute coronary syndromes

MS Sabatine, DA Morrow, RP Giugliano, PBJ Burton… - Circulation, 2005 - Am Heart Assoc
Background—In the setting of an acute coronary syndrome (ACS), anemia has the potential
to worsen myocardial ischemia; however, data relating anemia to clinical outcomes in ACS …

ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: a report of the American College of Cardiology/American Heart Association Task Force …

SC Smith Jr, TE Feldman, JW Hirshfeld Jr… - Journal of the American …, 2006 - Elsevier
The ACC/AHA Task Force on Practice Guidelines was formed to gather information and
make recommendations about appropriate use of technology for the diagnosis and …

Combination therapy with abciximab reduces angiographically evident thrombus in acute myocardial infarction: a TIMI 14 substudy

CM Gibson, JA de Lemos, SA Murphy, SJ Marble… - Circulation, 2001 - Am Heart Assoc
Background—Use of abciximab in combination with administration of thrombolytics has
been shown to improve epicardial and microvascular coronary blood flow in acute …

Facilitated PCI in patients with ST-elevation myocardial infarction

SG Ellis, M Tendera, MA de Belder… - … England Journal of …, 2008 - Mass Medical Soc
Background We hypothesized that percutaneous coronary intervention (PCI) preceded by
early treatment with abciximab plus half-dose reteplase (combination-facilitated PCI) or with …