Much of our knowledge on K+-channels was elucidated using specific peptide ligands
isolated from a number of venomous organisms. Recently, this field received a strong …

Calcium-activated potassium channels modulate calcium signaling cascades and
membrane potential in both excitable and non-excitable cells. In this article we will review …

Small conductance calcium-activated potassium (SK or K Ca 2) channels link intracellular
calcium transients to membrane potential changes. SK channel subtypes present different …

Potassium (K+) channels are a widespread superfamily of integral membrane proteins that
mediate selective transport of K+ ions through the cell membrane. They have been found in …

K+ channels are macromolecules embedded in biological membranes, where they play a
key role in cellular excitability and signal transduction pathways. Knowledge of their …

Scorpion toxins have been central to the investigation and understanding of the
physiological role of potassium (K+) channels and their expansive function in membrane …

A novel peptide, Cm39, was identified in the venom of the scorpion Centruroides
margaritatus. Its primary structure was determined. It consists of 37 amino acid residues with …

The biophysical properties of small conductance Ca 2+-activated K+(SK) channels are well
suited to underlie afterhyperpolarizations (AHPs) shaping the firing patterns of a …

Small conductance calcium-activated potassium (SK) channels are found in many types of
neurons as well as in some other cell types. These channels are selective for K+ and open …

Potassium channels regulate the membrane excitability of neurons, play a major role in
shaping action potentials, determining firing patterns and regulating neurotransmitter …