Applications and challenges of forensic proteomics
ED Merkley, DS Wunschel, KL Wahl… - Forensic science …, 2019 - Elsevier
Mass spectrometry-based proteomics has been a useful tool for addressing numerous
questions in basic biology research for many years. This success, combined with the …
questions in basic biology research for many years. This success, combined with the …
Medical Countermeasures against ricin intoxication
C Rasetti-Escargueil, A Avril - Toxins, 2023 - mdpi.com
Ricin toxin is a disulfide-linked glycoprotein (AB toxin) comprising one enzymatic A chain
(RTA) and one cell-binding B chain (RTB) contained in the castor bean, a Ricinus species …
(RTA) and one cell-binding B chain (RTB) contained in the castor bean, a Ricinus species …
A review of nutritional and toxicological implications of castor bean (Ricinus communis L.) meal in animal feeding systems
The nutrient‐rich defatted castor meal has been tested as a potential source of protein in
diets of many livestock species but has limitation due to challenges of toxins. This review …
diets of many livestock species but has limitation due to challenges of toxins. This review …
Multiplex quantification of protein toxins in human biofluids and food matrices using immunoextraction and high-resolution targeted mass spectrometry
M Dupré, B Gilquin, F Fenaille… - Analytical …, 2015 - ACS Publications
The development of rapid methods for unambiguous identification and precise quantification
of protein toxins in various matrices is essential for public health surveillance. Nowadays …
of protein toxins in various matrices is essential for public health surveillance. Nowadays …
Characterization of Ricin and R. communis Agglutinin Reference Materials
S Worbs, M Skiba, M Söderström, ML Rapinoja… - Toxins, 2015 - mdpi.com
Ricinus communis intoxications have been known for centuries and were attributed to the
toxic protein ricin. Due to its toxicity, availability, ease of preparation, and the lack of medical …
toxic protein ricin. Due to its toxicity, availability, ease of preparation, and the lack of medical …
Recommended immunological assays to screen for ricin-containing samples
S Simon, S Worbs, MA Avondet, DM Tracz, J Dano… - Toxins, 2015 - mdpi.com
Ricin, a toxin from the plant Ricinus communis, is one of the most toxic biological agents
known. Due to its availability, toxicity, ease of production and absence of curative treatments …
known. Due to its availability, toxicity, ease of production and absence of curative treatments …
Rapid, sensitive and reliable ricin identification in serum samples using LC–MS/MS
L Feldberg, E Elhanany, O Laskar, O Schuster - Toxins, 2021 - mdpi.com
Ricin, a protein derived from the seeds of the castor bean plant (Ricinus communis), is a
highly lethal toxin that inhibits protein synthesis, resulting in cell death. The widespread …
highly lethal toxin that inhibits protein synthesis, resulting in cell death. The widespread …
A protein standard absolute quantification strategy for enhanced absolute quantification of ricin in complex matrices using in vitro synthesized mutant holoprotein as …
LH Liang, YD Ma, Y Yang, HL Yu, JM Xia… - … of Chromatography A, 2023 - Elsevier
Ricin is a highly toxic protein toxin that poses a potential bioterrorism threat due to its
potency and widespread availability. However, the accurate quantification of ricin through …
potency and widespread availability. However, the accurate quantification of ricin through …
Rapid detection of abrin toxin and its isoforms in complex matrices by immuno-extraction and quantitative high resolution targeted mass spectrometry
EM Hansbauer, S Worbs, H Volland, S Simon… - Analytical …, 2017 - ACS Publications
Abrin expressed by the tropical plant Abrus precatorius is highly dangerous with an
estimated human lethal dose of 0.1–1 μg/kg body weight. Due to the potential misuse as a …
estimated human lethal dose of 0.1–1 μg/kg body weight. Due to the potential misuse as a …
Recommended mass spectrometry-based strategies to identify ricin-containing samples
SR Kalb, DM Schieltz, F Becher, C Astot… - Toxins, 2015 - mdpi.com
Ricin is a protein toxin produced by the castor bean plant (Ricinus communis) together with
a related protein known as R. communis agglutinin (RCA120). Mass spectrometric (MS) …
a related protein known as R. communis agglutinin (RCA120). Mass spectrometric (MS) …