Smart nanoparticles for cancer therapy

L Sun, H Liu, Y Ye, Y Lei, R Islam, S Tan… - Signal transduction and …, 2023 - nature.com
Smart nanoparticles, which can respond to biological cues or be guided by them, are
emerging as a promising drug delivery platform for precise cancer treatment. The field of …

Ribosome biogenesis in disease: new players and therapeutic targets

L Jiao, Y Liu, XY Yu, X Pan, Y Zhang, J Tu… - … and Targeted Therapy, 2023 - nature.com
The ribosome is a multi-unit complex that translates mRNA into protein. Ribosome
biogenesis is the process that generates ribosomes and plays an essential role in cell …

Near-infrared photoactivated nanomedicines for photothermal synergistic cancer therapy

H Sun, Q Zhang, J Li, S Peng, X Wang, R Cai - Nano Today, 2021 - Elsevier
Cancer nanomedicines have provided promising treatment strategies for the regression of
several types of cancer, although there still exists a need for significant advances to improve …

Aptamer‐protac conjugates (apcs) for tumor‐specific targeting in breast cancer

S He, F Gao, J Ma, H Ma, G Dong… - Angewandte …, 2021 - Wiley Online Library
Abstract Development of proteolysis targeting chimeras (PROTACs) is emerging as a
promising strategy for targeted protein degradation. However, the drug development using …

Dual active centers linked by a reversible electron station as a multifunctional nanozyme to induce synergetically enhanced cascade catalysis for tumor-specific …

Q Zhao, L Zheng, Y Gao, J Li, J Wei… - Journal of the …, 2023 - ACS Publications
Nanozymes have shown great promise in reactive oxygen species (ROS)-mediated tumor
therapy with mitigated side effects but are normally limited by the complex tumor …

Aptamer-modified Au nanoparticles: Functional nanozyme bioreactors for cascaded catalysis and catalysts for chemodynamic treatment of cancer cells

Y Ouyang, M Fadeev, P Zhang, R Carmieli, J Li… - ACS …, 2022 - ACS Publications
Polyadenine-stabilized Au nanoparticles (pA-AuNPs) reveal dual nanozyme catalytic
activities toward the H2O2-mediated oxidation of dopamine to aminochrome and toward the …

Recent progress and opportunities for nucleic acid aptamers

J Byun - Life, 2021 - mdpi.com
Coined three decades ago, the term aptamer and directed evolution have now reached their
maturity. The concept that nucleic acid could modulate the activity of target protein as ligand …

Detection of antibiotics in food: New achievements in the development of biosensors

M Majdinasab, RK Mishra, X Tang, JL Marty - TrAC Trends in Analytical …, 2020 - Elsevier
Antibiotics are extensively employed for preventive and curative purposes in animals. Their
accumulation in human body through food chain may induce serious health hazards …

Metal-organic frameworks (MOFs) as biomolecules drug delivery systems for anticancer purposes

M Coluccia, V Parisse, P Guglielmi, G Giannini… - European Journal of …, 2022 - Elsevier
Metal-organic frameworks (MOF) have been studied for infinite applications. Among these,
anticancer therapy has surely attracted great interest due to the intrinsic characteristics of …

Tumor microenvironment-triggered intratumoral in-situ biosynthesis of inorganic nanomaterials for precise tumor diagnostics

X Zhang, Q Zhao, J Yang, T Wang, F Chen… - Coordination Chemistry …, 2023 - Elsevier
The severe side effects and low bioavailability of conventional chemotherapeutic drugs are
the major problems that current clinical cancer treatments suffer from. In recent years, tumor …