The complex bidirectional communication between the gut and the brain is finely
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …

Within the last decade, research regarding the human gut microbiome has exploded. While
the gastrointestinal tract was once regarded simply as a digestive organ, new technologies …

Studies using animal models have shown that depression affects the stability of the
microbiota, but the actual structure and composition in patients with major depressive …

Early-life stress is a determinant of vulnerability to a variety of disorders that include
dysfunction of the brain and gut. Here we exploit a model of early-life stress, maternal …

Visceral pain is a global term used to describe pain originating from the internal organs of
the body, which affects a significant proportion of the population and is a common feature of …

There is a growing awareness of the potential for microbiota to influence gut‐brain
communication in health and disease. A variety of strategies have been used to study the …

Background About 10% of patients with IBS report the start of the syndrome after infectious
enteritis. The clinical features of postinfectious IBS (PI-IBS) resemble those of diarrhoea …

The gut–brain axis is the bidirectional communication between the gut and the brain, which
occurs through multiple pathways that include hormonal, neural and immune mediators. The …

Introduction As individuals age, the prevalence of neurocognitive and mental health
disorders increases. Current biomedical treatments do not completely address the …

Background Depression often coexists with the irritable bowel syndrome (IBS) which is
characterized by alterations in gut function. There is emerging evidence that the microbial …