Genetic epidemiology of breast cancer in Latin America
The last 10 years witnessed an acceleration of our understanding of what genetic factors
underpin the risk of breast cancer. Rare high-and moderate-penetrance variants such as …
underpin the risk of breast cancer. Rare high-and moderate-penetrance variants such as …
Mutations in BRCA1, BRCA2 and other breast and ovarian cancer susceptibility genes in Central and South American populations
Breast cancer (BC) is the most common malignancy among women worldwide. A major
advance in the understanding of the genetic etiology of BC was the discovery of BRCA1 and …
advance in the understanding of the genetic etiology of BC was the discovery of BRCA1 and …
[HTML][HTML] Human variability in glutathione-S-transferase activities, tissue distribution and major polymorphic variants: Meta-analysis and implication for chemical risk …
The input into the QIVIVE and Physiologically-Based kinetic and dynamic models of drug
metabolising enzymes performance and their inter-individual differences significantly …
metabolising enzymes performance and their inter-individual differences significantly …
Polymorphisms in GSTT1 and GSTM1 genes as possible risk factors for susceptibility to breast cancer development and their influence in chemotherapy response: a …
LM Pacholak, MK Amarante, RL Guembarovski… - Molecular Biology …, 2020 - Springer
Breast cancer (BC) is a heterogeneous and multifactorial disease. The system formed by
glutathione-S-transferases (GSTs) acts to protect the organism against the oxidative stress …
glutathione-S-transferases (GSTs) acts to protect the organism against the oxidative stress …
[HTML][HTML] Association analysis of rs1695 and rs1138272 variations in GSTP1 gene and breast cancer susceptibility
A Farmohammadi, V Arab-Yarmohammadi… - Asian Pacific Journal …, 2020 - ncbi.nlm.nih.gov
Background: The glutathione S transferases P1 (GSTP1) is one of the common type of the
GSTs family. This gene has several genetic polymorphisms that the rs1695 and rs1138272 …
GSTs family. This gene has several genetic polymorphisms that the rs1695 and rs1138272 …
GSTM3 function and polymorphism in cancer: emerging but promising
S Wang, J Yang, L You, M Dai… - Cancer management and …, 2020 - Taylor & Francis
Cancer is a major cause of human mortality; however, the molecular mechanisms and
proteomic biomarkers that cause tumor progression in malignant tumors are either unknown …
proteomic biomarkers that cause tumor progression in malignant tumors are either unknown …
Association of glutathione S-transferase T1, M1, and P1 polymorphisms in the breast cancer risk: a meta-analysis
Z Song, C Shao, C Feng, Y Lu, Y Gao… - … and clinical risk …, 2016 - Taylor & Francis
Background Several case–control studies investigating the relationship between genetic
polymorphisms of glutathione S-transferase (GST) M1, GSTT1, and GSTP1 (rs1695) and the …
polymorphisms of glutathione S-transferase (GST) M1, GSTT1, and GSTP1 (rs1695) and the …
The importance of polymorphisms in the genes encoding glutathione S-transferase isoenzymes in development of selected cancers and cardiovascular diseases
K Grussy, M Łaska, W Moczurad… - Molecular Biology …, 2023 - Springer
Glutathione S-transferases are a family of enzymes, whose main role is to detoxify cells from
many exogenous factors, such as xenobiotics or carcinogens. It has also been proven that …
many exogenous factors, such as xenobiotics or carcinogens. It has also been proven that …
Association of GSTP1 p. Ile105Val (rs1695, c. 313A> G) variant with the risk of breast carcinoma among Egyptian women
Several reports examined the association of the GSTP1 p. Ile105Val (rs1695, c. 313A> G)
variant with the elevated risk of multiple cancerous diseases involving breast carcinoma, but …
variant with the elevated risk of multiple cancerous diseases involving breast carcinoma, but …
CYP1A1, CYP1B1, GSTM1 and GSTT1 genetic variants and breast cancer risk in Mexican women
A García-Martínez, B Gamboa-Loira… - salud pública de …, 2017 - SciELO Public Health
Objective: To evaluate if variants in the genes CYP1A1 (T3801C and A4889G), CYP1B1
(G119T), GSTM1 (indel) and GSTT1 (indel) are associated with breast cancer (BC) among …
(G119T), GSTM1 (indel) and GSTT1 (indel) are associated with breast cancer (BC) among …