Surgery for cancer: a trigger for metastases
S Tohme, RL Simmons, A Tsung - Cancer research, 2017 - AACR
Surgery is a crucial intervention and provides a chance of cure for patients with cancer. The
perioperative period is characterized by an increased risk for accelerated growth of …
perioperative period is characterized by an increased risk for accelerated growth of …
Exploiting the critical perioperative period to improve long-term cancer outcomes
M Horowitz, E Neeman, E Sharon… - Nature reviews Clinical …, 2015 - nature.com
Evidence suggests that the perioperative period and the excision of the primary tumour can
promote the development of metastases—the main cause of cancer-related mortality. This …
promote the development of metastases—the main cause of cancer-related mortality. This …
Aggressive intraoperative warming versus routine thermal management during non-cardiac surgery (PROTECT): a multicentre, parallel group, superiority trial
DI Sessler, L Pei, K Li, S Cui, MTV Chan, Y Huang… - The Lancet, 2022 - thelancet.com
Background Moderate intraoperative hypothermia promotes myocardial injury, surgical site
infections, and blood loss. Whether aggressive warming to a truly normothermic temperature …
infections, and blood loss. Whether aggressive warming to a truly normothermic temperature …
Active body surface warming systems for preventing complications caused by inadvertent perioperative hypothermia in adults
E Madrid, G Urrútia, MR i Figuls… - Cochrane Database …, 2016 - cochranelibrary.com
Background Inadvertent perioperative hypothermia is a phenomenon that can occur as a
result of the suppression of the central mechanisms of temperature regulation due to …
result of the suppression of the central mechanisms of temperature regulation due to …
Multimodal approach to control postoperative pathophysiology and rehabilitation
H Kehlet - British journal of anaesthesia, 1997 - Elsevier
Major surgery is still associated with undesirable sequelae such as pain, cardiopulmonary,
infective and thromboembolic complications, cerebral dysfunction, nausea and …
infective and thromboembolic complications, cerebral dysfunction, nausea and …
[HTML][HTML] Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization
A Kurz, DI Sessler, R Lenhardt - New England Journal of …, 1996 - Mass Medical Soc
Background Mild perioperative hypothermia, which is common during major surgery, may
promote surgical-wound infection by triggering thermoregulatory vasoconstriction, which …
promote surgical-wound infection by triggering thermoregulatory vasoconstriction, which …
Multimodal strategies to improve surgical outcome
H Kehlet, DW Wilmore - The American journal of surgery, 2002 - Elsevier
Objective: To evaluate the effect of modifying perioperative care in noncardiac surgical
patients on morbidity, mortality, and other outcome measures. Background: New …
patients on morbidity, mortality, and other outcome measures. Background: New …
Perioperative maintenance of normothermia reduces the incidence of morbid cardiac events: a randomized clinical trial
SM Frank, LA Fleisher, MJ Breslow, MS Higgins… - Jama, 1997 - jamanetwork.com
Objective.—To assess the relationship between body temperature and cardiac morbidity
during the perioperative period. Design.—Randomized controlled trial comparing routine …
during the perioperative period. Design.—Randomized controlled trial comparing routine …
Impact of the World Health Organization surgical safety checklist on patient safety
AS Haugen, N Sevdalis, E Søfteland - Anesthesiology, 2019 - pubs.asahq.org
The incidence of surgical complications has remained largely unchanged over the past two
decades. Inherent complexity in surgery, new technology possibilities, increasing age and …
decades. Inherent complexity in surgery, new technology possibilities, increasing age and …