Dietary flavonoids interaction with CREB-BDNF pathway: An unconventional approach for comprehensive management of epilepsy

P Sharma, A Kumar, D Singh - Current neuropharmacology, 2019 - ingentaconnect.com
cAMP response element binding protein (CREB) is a key transcriptional regulator that
regulates the transcription of genes related with neuronal differentiation, synaptic plasticity …

Эпилепсия у детей и взрослых женщин и мужчин

ВА Карлов - 2019 - elibrary.ru
В руководстве представлены результаты 60-летней работы автора в области детской
и взрослой неврологии и эпилептологии. Впервые эпилептология представлена в …

[HTML][HTML] Antiepileptic drugs in development pipeline: a recent update

H Kaur, B Kumar, B Medhi - Eneurologicalsci, 2016 - Elsevier
Epilepsy is the most common neurological disorder which significantly affects the quality of
life and poses a health as well as economic burden on society. Epilepsy affects …

Efflux dynamics of the antiseizure drug, levetiracetam, through the P-glycoprotein channel revealed by advanced comparative molecular simulations

E Behmard, E Barzegari, S Najafipour, A Kouhpayeh… - Scientific reports, 2022 - nature.com
Understanding the precise mechanistic details of the possible binding and transport of
antiseizure medications (ASMs) through the P-glycoprotein (P-gp) efflux pump is essential to …

[HTML][HTML] Evaluation of anti-epileptic activity of leaf extracts of Punica granatum on experimental models of epilepsy in mice

GL Viswanatha, MV Venkataranganna… - Journal of …, 2016 - ncbi.nlm.nih.gov
Objectives: This study was aimed to examine the anti-epileptic activity of leaf extracts of
Punica granatum in experimental models of epilepsy in Swiss albino mice. Materials and …

Central nervous system activities of indole derivatives: An overview

T Saini, S Kumar, B Narasimhan - Central Nervous System …, 2016 - ingentaconnect.com
Indole and its derivatives are continuously drawing interest of researchers in the field of
medicinal chemistry for development of newer significant moieties due to their wide range of …

Loss of neurosteroid-mediated protection following stress during fetal life

JJ Hirst, AL Cumberland, JC Shaw, GA Bennett… - The Journal of Steroid …, 2016 - Elsevier
Elevated levels of neurosteroids during late gestation protect the fetal brain from
hypoxia/ischaemia and promote neurodevelopment. Suppression of allopregnanolone …

Deciphering the role of metal and non-metals in the treatment of epilepsy

R Sande, G Doshi, A Godad - Neurochemistry International, 2023 - Elsevier
Metals and non-metals have known to play a significant role in various physiological roles in
the body including the central nervous system (CNS). The alterations in their concentration …

Eslicarbazepine acetate add‐on therapy for drug‐resistant focal epilepsy

XC Chang, H Yuan, Y Wang, HQ Xu… - Cochrane Database …, 2021 - cochranelibrary.com
Eslicarbazepine acetate add‐on therapy for drug‐resistant focal epilepsy - Chang, XC - 2021 |
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[HTML][HTML] 3, 4, 5-Trimethoxycinnamic acid, one of the constituents of Polygalae Radix exerts anti-seizure effects by modulating GABAAergic systems in mice

CY Chen, XD Wei, CR Chen - Journal of pharmacological sciences, 2016 - Elsevier
Polygalae Radix is an important medicinal plant that is widely used in most of Africa. 3, 4, 5-
Trimethoxycinnamic acid (TMCA) is one of the constituents of Polygalae Radix. Until now …