Nanomedicine has emerged as a promising mean to improve theranostic efficacy and
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …

Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

Carbon dots, a recent member of the renowned carbon-based nanomaterials family, have
attracted significant interest from various fields. The extraordinary properties, including …

Brain delivery is one of the major challenges in drug development because of the high
number of patients suffering from neural diseases and the low efficiency of the treatments …

Owing to the complex and still not fully understood physiological environment, the
development of traditional nanosized drug delivery systems is very challenging for precision …

Targeted delivery of therapeutic agents is an important way to improve the therapeutic index
and reduce side effects. To design nanoparticles for targeted delivery, both enhanced tumor …

Cell-penetrating peptides (CPPs), also known as protein translocation domains, membrane
translocating sequences or Trojan peptides, are small molecules of 6 to 30 amino acid …

Gliomas are the most common tumor of the central nervous system. However, the presence
of the brain barrier blocks the effective delivery of drugs and leads to the treatment failure of …

Abstract Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past
few years. It is widely explored in drug delivery, where the development of nanomedicines …

Extracellular deposition of β-amyloid (Aβ) peptide aggregates is a major characteristic of
Alzheimer's disease (AD) brain. Because Aβ peptide aggregates aggravate neuropathy and …