Circulating tumor cells (CTCs) are tumor cells that have sloughed off the primary tumor and
extravasate into and circulate in the blood. Understanding of the metastatic cascade of CTCs …

In the fight against cancer, early detection is a key factor for successful treatment. However,
the detection of cancer in the early stage has been hindered by the intrinsic limits of …

Cancer biomarkers have transformed current practices in the oncology clinic. Continued
discovery and validation are crucial for improving early diagnosis, risk stratification, and …

Hepatocellular carcinoma (HCC) is among the leading causes of worldwide cancer‐related
morbidity and mortality. Poor prognosis of HCC is attributed primarily to tumor presentation …

Simple Summary Circulating tumour cells (CTCs) are cancer cells shed into the bloodstream
from tumours and their analysis can provide important insights into cancer detection and …

Circulating tumor cells, a component of the “liquid biopsy”, hold great potential to transform
the current landscape of cancer therapy. A key challenge to unlocking the clinical utility of …

The importance of early cancer diagnosis and improved cancer therapy has been clear for
years and has initiated worldwide research towards new possibilities in the care strategy of …

The ability to study nonhematologic cancers through noninvasive sampling of blood is one
of the most exciting and rapidly advancing fields in cancer diagnostics. This has been driven …

Metastasis formation is the main cause of cancer-related death in patients with solid
tumours. At the beginning of this process, cancer cells escape from the primary tumour to the …

Genome-wide transcriptome analyses are routinely used to monitor tissue-, disease-and cell
type–specific gene expression, but it has been technically challenging to generate …