As part of their life cycle, neutralophilic bacteria are often exposed to varying environmental
stresses, among which fluctuations in pH are the most frequent. In particular, acid …

The extracellular matrix is an integral part of microbial biofilms and an important field of
research. Confocal laser scanning microscopy is a valuable tool for the study of biofilms, and …

Cell dormancy is a widespread mechanism used by bacteria to evade environmental
threats, including antibiotics. Here we monitored bacterial antibiotic tolerance and regrowth …

Recent advances in quantitative single-cell analysis revealed large diversity in gene
expression levels between individual cells, which could affect the physiology and/or fate of …

Klebsiella pneumoniae, Escherichia coli, and other members of the Enterobacteriaceae
family are common human pathogens that have acquired broad antibiotic resistance …

Many carbon-fixing bacteria rely on a CO2 concentrating mechanism (CCM) to elevate the
CO2 concentration around the carboxylating enzyme ribulose bisphosphate carboxylase …

The Earth is home to environments characterized by low pH, including the gastrointestinal
tract of vertebrates and large areas of acidic soil. Most bacteria are neutralophiles, but can …

Synthetic biology allows us to reuse, repurpose, and reconfigure biological systems to
address society's most pressing challenges. Developing biotechnologies in this way …

Antibiotic persistence describes the presence of phenotypic variants within an isogenic
bacterial population that are transiently tolerant to antibiotic treatment. Perturbations of …

Unlike eukaryotes, bacteria undergo large changes in osmolality and cytoplasmic pH. It has
been described that during acid stress, bacteria internal pH promptly acidifies, followed by …