Strong evidence now supports the adoption of cervical cancer prevention strategies that
explicitly focus on persistent infection with the causal agent, human papillomavirus (HPV) …

Cervical cancer is the second most common cancer in women worldwide, and knowledge
regarding its cause and pathogenesis is expanding rapidly. Persistent infection with one of …

Background The natural history of human papillomavirus (HPV) infections in older women is
critical for preventive strategies, including vaccination and screening intervals, but is poorly …

This chapter suggests promising areas of future epidemiologic research on human
papillomavirus (HPV) and anogenital cancer, organized around our understanding of …

The major steps in cervical carcinogenesis include infection of the metaplastic epithelium of
the cervical transformation zone with one or more of the 12–18 carcinogenic types of human …

Background. Cervical cancer is caused by persistent infection with human papillomavirus
(HPV). Most infections and associated lesions clear spontaneously. It is important to define …

Oncogenic HPV types are the major cause of worldwide cervical cancer, but only a small
proportion of infected women will develop high‐grade cervical intraepithelial neoplasia or …

A causal link between chronic inflammation and carcinogenesis is explored by reviewing
illustrative examples of specific cancers and causal agents and mechanisms. The causal …

Approximately 15 types of human papillomavirus (HPV) infection cause virtually all cases of
cervical cancer. Human papillomavirus 16 is the major type, accounting for approximately …

Over the past several decades, knowledge of the biology and epidemiology of human
papillomavirus (HPV) infection has increased tremendously. However, there are still many …