Motor neurons (MNs) are neuronal cells located in the central nervous system (CNS)
controlling a variety of downstream targets. This function infers the existence of MN subtypes …

The formation of highly efficient and reliable synapses at the neuromuscular junction (NMJ)
relies on dynamic molecular interactions. Studies of the development and maturation of the …

Abstract Specification of cell identity during development depends on exposure of cells to
sequences of extrinsic cues delivered at precise times and concentrations. Identification of …

Motor units are the fundamental elements responsible for muscle movement. They are
formed by lower motor neurons and their muscle targets, synapsed via neuromuscular …

Brain functions rely on specific patterns of connectivity. Teneurins are evolutionarily
conserved transmembrane proteins that instruct synaptic partner matching in Drosophila …

Axons follow highly stereotyped and reproducible trajectories to their targets. In this review
we address the properties of the first pioneer neurons to grow in the developing nervous …

Dysfunction of microRNA (miRNA) metabolism is thought to underlie diseases affecting
motoneurons. One miRNA, miR-218, is abundantly and selectively expressed by developing …

Growing axons encounter multiple guidance cues, but it is unclear how separate signals are
resolved and integrated into coherent instructions for growth cone navigation. We report that …

Neuronal growth cones are exquisite sensory-motor machines capable of transducing
features contacted in their local extracellular environment into guided process extension …

Emerging evidence in the literature describes a physical and functional association between
the neural and skeletal systems that forms a neuro-osteogenic network. This communication …